Mathematical modelling approaches have become increasingly abundant in cancer
research. The complexity of cancer is well suited to quantitative approaches as it provides …

Aneuploidy is a hallmark of breast cancer; however, knowledge of how these complex
genomic rearrangements evolve during tumorigenesis is limited. In this study, we developed …

Cancer is a leading cause of death worldwide and represents one of the biggest biomedical
research challenges of our time. Tumor progression is caused by somatic evolution of cell …

The poor prognosis of glioma patients brought attention to the need for effective therapeutic
approaches for precision therapy. Here, we deployed algorithms relying on network …

Background Triple-negative breast cancer lacks estrogen, progesterone, and HER2
receptors and is thus not possible to treat with targeted therapies for these receptors …

It has been declared repeatedly that cancer is a result of molecular genetic abnormalities.
However, there has been no working model describing the specific functional consequences …

Recently available cancer sequencing data have revealed a complex view of the cancer
genome containing a multitude of mutations, including drivers responsible for cancer …

Background Cancer is a complex disease which is characterized by the accumulation of
genetic alterations during the patient's lifetime. With the development of the next-generation …

Colon cancer is one of the most common malignancies and its etiology closely tied to dietary
habits. Recent epidemiological data shows that colon cancer incidence is shifting to a much …

Motivation Breast cancer is the most commonly diagnosed malignancy in women and the
second cause of cancer death in developed countries. While advancements in early …