[HTML][HTML] The molecular athlete: exercise physiology from mechanisms to medals
Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …
Training-induced changes in mitochondrial content and respiratory function in human skeletal muscle
A sedentary lifestyle has been linked to a number of metabolic disorders that have been
associated with sub-optimal mitochondrial characteristics and an increased risk of …
associated with sub-optimal mitochondrial characteristics and an increased risk of …
Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy
Mitochondrial health is critical for skeletal muscle function and is improved by exercise
training through both mitochondrial biogenesis and removal of damaged/dysfunctional …
training through both mitochondrial biogenesis and removal of damaged/dysfunctional …
High-intensity exercise and mitochondrial biogenesis: current controversies and future research directions
It is well established that different types of exercise can provide a powerful stimulus for
mitochondrial biogenesis. However, there are conflicting findings in the literature, and a …
mitochondrial biogenesis. However, there are conflicting findings in the literature, and a …
Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy
Mitochondria form a complex, interconnected reticulum that is maintained through
coordination among biogenesis, dynamic fission, and fusion and mitophagy, which are …
coordination among biogenesis, dynamic fission, and fusion and mitophagy, which are …
Exercise-induced autophagy suppresses sarcopenia through Akt/mTOR and Akt/FoxO3a signal pathways and AMPK-mediated mitochondrial quality control
Z Zeng, J Liang, L Wu, H Zhang, J Lv… - Frontiers in physiology, 2020 - frontiersin.org
Exercise training is one of the most effective interventional strategies for sarcopenia in aged
people. Nevertheless, the underlying mechanisms are not well recognized. Increasing …
people. Nevertheless, the underlying mechanisms are not well recognized. Increasing …
A systematic review of p53 regulation of oxidative stress in skeletal muscle
K Beyfuss, DA Hood - Redox Report, 2018 - Taylor & Francis
Background: p53 is a tumor suppressor protein involved in regulating a wide array of
signaling pathways. The role of p53 in the cell is determined by the type of imposed …
signaling pathways. The role of p53 in the cell is determined by the type of imposed …
The active grandparent hypothesis: Physical activity and the evolution of extended human healthspans and lifespans
The proximate mechanisms by which physical activity (PA) slows senescence and
decreases morbidity and mortality have been extensively documented. However, we lack an …
decreases morbidity and mortality have been extensively documented. However, we lack an …
Exercise and exercise training‐induced increase in autophagy markers in human skeletal muscle
N Brandt, TP Gunnarsson, J Bangsbo… - Physiological …, 2018 - Wiley Online Library
Moderately trained male subjects (mean age 25 years; range 19–33 years) completed an 8‐
week exercise training intervention consisting of continuous moderate cycling at 157±20 W …
week exercise training intervention consisting of continuous moderate cycling at 157±20 W …
Principles of exercise prescription, and how they influence exercise-induced changes of transcription factors and other regulators of mitochondrial biogenesis
Physical inactivity represents the fourth leading risk factor for mortality, and it has been
linked with a series of chronic disorders, the treatment of which absorbs~ 85% of healthcare …
linked with a series of chronic disorders, the treatment of which absorbs~ 85% of healthcare …