Background: General pathophysiological mechanisms regarding associations between fluid
administration and intra-abdominal hypertension (IAH) are evident, but specific effects of …

Correction of intravascular hypovolemia is a key component of the prevention and
management of acute kidney injury (AKI), but excessive fluid administration is associated …

In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the
classification and management of acute kidney injury (AKI). The guideline was derived from …

Purpose We compared a restrictive fluid management strategy to usual care among critically
ill patients with acute kidney injury (AKI) who had received initial fluid resuscitation. Methods …

In this review, we aimed to comprehensively summarize current literature on
pathophysiology, relevance, diagnosis and treatment of fluid accumulation in patients with …

Purpose After cardiac surgery, fluid bolus therapy (FBT) with 20% human albumin may
facilitate less fluid and vasopressor administration than FBT with crystalloids. We aimed to …

Albumin is the most abundant and perhaps most important protein in human blood.
Research has identified many of albumin's possible roles in modulating acid-base balance …

Objective Positive fluid balance is common among critically ill patients and leads to worse
outcomes, particularly in sepsis, acute respiratory distress syndrome, and acute kidney …

Intravenous administration of crystalloid or colloid solutions is the most common intervention
for correcting hypovolemia in intensive care unit patients. In critical illness, especially sepsis …

Septic shock is the most severe form of sepsis, characterized by (a) persistent hypotension
despite fluid resuscitation and (b) the presence of tissue hypoperfusion. Delays in the …