Plasmid fitness costs are caused by specific genetic conflicts enabling resolution by compensatory mutation

JPJ Hall, RCT Wright, E Harrison, KJ Muddiman… - PLoS …, 2021 - journals.plos.org
Plasmids play an important role in bacterial genome evolution by transferring genes
between lineages. Fitness costs associated with plasmid carriage are expected to be a …

[HTML][HTML] Myths and misconceptions around antibiotic resistance: time to get rid of them

CF Amábile-Cuevas - Infection & Chemotherapy, 2022 - ncbi.nlm.nih.gov
The antibiotic resistance arena is fraught with myths and misconceptions, leading to wrong
strategies to combat it. It is crucial to identify them, discuss them in light of current evidence …

Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance

R Salamzade, AL Manson, BJ Walker… - Genome medicine, 2022 - Springer
Abstract Background Carbapenem-resistant Enterobacterales (CRE) are an urgent global
health threat. Inferring the dynamics of local CRE dissemination is currently limited by our …

[HTML][HTML] Dominant carbapenemase-encoding plasmids in clinical Enterobacterales isolates and hypervirulent Klebsiella pneumoniae, Singapore

M Yong, Y Chen, G Oo, KC Chang… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
Dissemination of carbapenemase-encoding plasmids by horizontal gene transfer in
multidrug-resistant bacteria is the major driver of rising carbapenem-resistance, but the …

A chromosomal mutation is superior to a plasmid-encoded mutation for plasmid fitness cost compensation

RCT Wright, AJ Wood, MJ Bottery, KJ Muddiman… - PLoS …, 2024 - journals.plos.org
Plasmids are important vectors of horizontal gene transfer in microbial communities but can
impose a burden on the bacteria that carry them. Such plasmid fitness costs are thought to …

Expression of a novel class of bacterial Ig-like proteins is required for IncHI plasmid conjugation

M Hüttener, A Prieto, S Aznar, M Bernabeu… - PLoS …, 2019 - journals.plos.org
Antimicrobial resistance (AMR) is currently one of the most important challenges to the
treatment of bacterial infections. A critical issue to combat AMR is to restrict its spread. In …

Tolerancia al triclosán en cepas de Klebsiella pneumoniae y Escherichia coli de origen clínico

Y Sánchez-Neira… - Revista …, 2021 - revistasdigitales.uniboyaca.edu.co
Introducción: Los biocidas son compuestos químicos que se emplean comúnmente para
inhibir o eliminar el crecimiento microbiano. El triclosán es un agente biocida que afecta la …

[PDF][PDF] Tolerancia al triclosán en cepas de Klebsiella pneumoniae y Escherichia coli de origen clínico

YS Neira, EXU Cáceres… - … Ciencias de la Salud de la …, 2021 - scholar.archive.org
Introducción: Los biocidas son compuestos químicos que se emplean comúnmente para
inhibir o eliminar el crecimiento microbiano. El triclosán es un agente biocida que afecta la …

Expression of a novel class of bacterial Ig-like proteins is required for IncHI plasmid conjugation

M Hüttener Queiroz, A Prieto Durán… - PLoS Genetics, 2019 …, 2019 - diposit.ub.edu
Antimicrobial resistance (AMR) is currently one of the most important challenges to the
treatment of bacterial infections. A critical issue to combat AMR is to restrict its spread. In …