Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition
KM Hanssen, M Haber, JI Fletcher - Drug Resistance Updates, 2021 - Elsevier
Resistance to chemotherapy remains one of the most significant obstacles to successful
cancer treatment. While inhibiting drug efflux mediated by ATP-binding cassette (ABC) …
cancer treatment. While inhibiting drug efflux mediated by ATP-binding cassette (ABC) …
ABCG2: determining its relevance in clinical drug resistance
RW Robey, O Polgar, J Deeken, KW To… - Cancer and Metastasis …, 2007 - Springer
Multidrug resistance is a major obstacle to successful cancer treatment. One mechanism by
which cells can become resistant to chemotherapy is the expression of ABC transporters that …
which cells can become resistant to chemotherapy is the expression of ABC transporters that …
Mechanisms of multidrug resistance in cancer
JP Gillet, MM Gottesman - Multi-drug resistance in cancer, 2010 - Springer
The development of multidrug resistance (MDR) to chemotherapy remains a major
challenge in the treatment of cancer. Resistance exists against every effective anticancer …
challenge in the treatment of cancer. Resistance exists against every effective anticancer …
Role of ABCG2/BCRP in biology and medicine
P Krishnamurthy, JD Schuetz - Annu. Rev. Pharmacol. Toxicol., 2006 - annualreviews.org
▪ Abstract The protein variously named ABCG2/BCRP/MXR/ABCP is a recently described
ATP-binding cassette (ABC) transporter originally identified by its ability to confer drug …
ATP-binding cassette (ABC) transporter originally identified by its ability to confer drug …
MRP1 and its role in anticancer drug resistance
JF Lu, D Pokharel, M Bebawy - Drug metabolism reviews, 2015 - Taylor & Francis
The phenomenon of multidrug resistance (MDR) in cancer is associated with the
overexpression of the ATP-binding cassette (ABC) transporter proteins, including multidrug …
overexpression of the ATP-binding cassette (ABC) transporter proteins, including multidrug …
Revisiting the ABCs of multidrug resistance in cancer chemotherapy
The adenosine triphosphate binding cassette (ABC) transporters are one of the largest
transmembrane gene families in humans. The ABC transporters are present in a number of …
transmembrane gene families in humans. The ABC transporters are present in a number of …
ABCG2: structure, function and role in drug response
O Polgar, RW Robey, SE Bates - Expert opinion on drug …, 2008 - Taylor & Francis
ABCG2 was discovered in multi-drug-resistant cancer cells, with the identification of
chemotherapeutic agents, such as mitoxantrone, flavopiridol, methotrexate and irinotecan as …
chemotherapeutic agents, such as mitoxantrone, flavopiridol, methotrexate and irinotecan as …
Photoactivated H2 Nanogenerator for Enhanced Chemotherapy of Bladder Cancer
R Sun, X Liu, G Li, H Wang, Y Luo, G Huang, X Wang… - ACS …, 2020 - ACS Publications
Hydrogen gas can mitigate oxidative stress in many diseases and is regarded to be safe and
free of side effects. Inspired by a metalloenzyme in a variety of microorganisms, here, we …
free of side effects. Inspired by a metalloenzyme in a variety of microorganisms, here, we …
ABCG2: the key to chemoresistance in cancer stem cells?
Y An, WM Ongkeko - Expert opinion on drug metabolism & …, 2009 - Taylor & Francis
Multi-drug chemoresistance remains one of the most common reasons for chemotherapy
failure. The membrane transporter protein ABCG2/BCRP1 has been shown in vitro to …
failure. The membrane transporter protein ABCG2/BCRP1 has been shown in vitro to …
Prognostic markers for bladder cancer: International Consensus Panel on bladder tumor markers
T Habuchi, M Marberger, MJ Droller, GP Hemstreet III… - Urology, 2005 - Elsevier
The International Consensus Panel on cytology and bladder tumor markers evaluated
markers that have the ability to predict tumor recurrence, progression, development of …
markers that have the ability to predict tumor recurrence, progression, development of …