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Attention-deficit/hyperactive disorder updates
M Kessi, H Duan, J **ong, B Chen, F He… - Frontiers in molecular …, 2022 - frontiersin.org
Background Attention-deficit/hyperactive disorder (ADHD) is a neurodevelopmental disorder
that commonly occurs in children with a prevalence ranging from 3.4 to 7.2%. It profoundly …
that commonly occurs in children with a prevalence ranging from 3.4 to 7.2%. It profoundly …
Striatal cholinergic interneuron regulation and circuit effects
The striatum plays a central role in motor control and motor learning. Appropriate responses
to environmental stimuli, including pursuit of reward or avoidance of aversive experience all …
to environmental stimuli, including pursuit of reward or avoidance of aversive experience all …
New insights into cholinergic neuron diversity
Cholinergic neurons comprise a small population of cells in the striatum but have
fundamental roles in fine tuning brain function, and in the etiology of neurological and …
fundamental roles in fine tuning brain function, and in the etiology of neurological and …
Checks and balances on cholinergic signaling in brain and body function
A century after the discovery of acetylcholine (ACh), we recognize both ACh receptors,
transporters, and synthesizing and degrading enzymes and regulators of their expression as …
transporters, and synthesizing and degrading enzymes and regulators of their expression as …
Recurrent implication of striatal cholinergic interneurons in a range of neurodevelopmental, neurodegenerative, and neuropsychiatric disorders
Cholinergic interneurons are “gatekeepers” for striatal circuitry and play pivotal roles in
attention, goal-directed actions, habit formation, and behavioral flexibility. Accordingly …
attention, goal-directed actions, habit formation, and behavioral flexibility. Accordingly …
[HTML][HTML] Functional and biochemical consequences of disease variants in neurotransmitter transporters: a special emphasis on folding and trafficking deficits
Neurotransmitters, such as γ-aminobutyric acid, glutamate, acetyl choline, glycine and the
monoamines, facilitate the crosstalk within the central nervous system. The designated …
monoamines, facilitate the crosstalk within the central nervous system. The designated …
The neuroscience of cognitive-motivational styles: Sign-and goal-trackers as animal models.
Cognitive-motivational styles describe predominant patterns of processing or biases that
broadly influence human cognition and performance. Here we focus on the impact of …
broadly influence human cognition and performance. Here we focus on the impact of …
A systematic review and meta-analysis of chemical exposures and attention-deficit/hyperactivity disorder in children
Exposure to certain chemicals prenatally and in childhood can impact development and may
increase risk for attention-deficit/hyperactivity disorder (ADHD). Leveraging a larger set of …
increase risk for attention-deficit/hyperactivity disorder (ADHD). Leveraging a larger set of …
Impaired presynaptic high-affinity choline transporter causes a congenital myasthenic syndrome with episodic apnea
S Bauché, S O'regan, Y Azuma, F Laffargue… - The American Journal of …, 2016 - cell.com
The neuromuscular junction (NMJ) is one of the best-studied cholinergic synapses. Inherited
defects of peripheral neurotransmission result in congenital myasthenic syndromes (CMSs) …
defects of peripheral neurotransmission result in congenital myasthenic syndromes (CMSs) …
Nicotine addiction and psychiatric disorders
Even though smoking rates have long been on the decline, nicotine addiction still affects
20% of the US population today. Moreover, nicotine dependence shows high comorbidity …
20% of the US population today. Moreover, nicotine dependence shows high comorbidity …