Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …
more than 500 million population worldwide. OA was believed to be caused by the wearing …
[HTML][HTML] Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment
M Zhang, W Hu, C Cai, Y Wu, J Li, S Dong - Materials Today Bio, 2022 - Elsevier
Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …
[HTML][HTML] Chondrocyte ferroptosis contribute to the progression of osteoarthritis
X Yao, K Sun, S Yu, J Luo, J Guo, J Lin, G Wang… - Journal of orthopaedic …, 2021 - Elsevier
Background Osteoarthritis (OA) is a complex process comprised of mechanical load,
inflammation, and metabolic factors. It is still unknown that if chondrocytes undergo …
inflammation, and metabolic factors. It is still unknown that if chondrocytes undergo …
[HTML][HTML] Chondrocyte-specific genomic editing enabled by hybrid exosomes for osteoarthritis treatment
Y Liang, X Xu, L Xu, Z Iqbal, K Ouyang, H Zhang… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: A cell-specific delivery vehicle is required to achieve gene editing of the disease-
associated cells, so the hereditable genome editing reactions are confined within these cells …
associated cells, so the hereditable genome editing reactions are confined within these cells …
The association between systemic immune-inflammation index and rheumatoid arthritis: evidence from NHANES 1999–2018
B Liu, J Wang, Y Li, K Li, Q Zhang - Arthritis research & therapy, 2023 - Springer
Purpose We aimed to explore the relationship between the systemic immune-inflammation
index (SII) and rheumatoid arthritis (RA) using NHANES from 1999 to 2018. Methods We …
index (SII) and rheumatoid arthritis (RA) using NHANES from 1999 to 2018. Methods We …
A review of the effects of collagen treatment in clinical studies
H Wang - Polymers, 2021 - mdpi.com
Collagen, an abundant extracellular matrix protein, has been found to have a lot of
pharmaceuticals, medicine, food, and cosmetics applications. Increased knowledge of …
pharmaceuticals, medicine, food, and cosmetics applications. Increased knowledge of …
[HTML][HTML] Silk fibroin-based biomaterials for cartilage/osteochondral repair
Z Zhou, J Cui, S Wu, Z Geng, J Su - Theranostics, 2022 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a common joint disease with a high disability rate. In addition, OA not
only causes great physiological and psychological harm to patients, but also puts great …
only causes great physiological and psychological harm to patients, but also puts great …
Cartilage tissue engineering: From proinflammatory and anti‑inflammatory cytokines to osteoarthritis treatments
S Liu, Z Deng, K Chen, S Jian… - Molecular …, 2022 - spandidos-publications.com
Osteoarthritis (OA), one of the most common joint diseases, is characterized by fibrosis,
rhagadia, ulcers and attrition of articular cartilage due to a number of factors. The etiology of …
rhagadia, ulcers and attrition of articular cartilage due to a number of factors. The etiology of …
Osteoarthritis: New insight on its pathophysiology
Understanding of the basis of osteoarthritis (OA) has seen some interesting advancements
in recent years. It has been observed that cartilage degeneration is preceded by …
in recent years. It has been observed that cartilage degeneration is preceded by …
Role of reactive oxygen species in aging and age-related diseases: A review
Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …