The LOD paradox: when lower isn't always better in biosensor research and development

H Moulahoum, F Ghorbanizamani - Biosensors and Bioelectronics, 2024 - Elsevier
Biosensor research has long focused on achieving the lowest possible Limits of Detection
(LOD), driving significant advances in sensitivity and opening up new possibilities in …

Development of Nucleic‐Acid‐Based Electrochemical Biosensors for Clinical Applications

Z Zhang, P Sen, BR Adhikari, Y Li… - Angewandte …, 2022 - Wiley Online Library
Nucleic acids are remarkable molecules. In addition to Watson–Crick base pairing, the
different structural motifs of these molecules can bind non‐nucleic acid targets or catalyze …

[HTML][HTML] Strategies and perspectives to develop SARS-CoV-2 detection methods and diagnostics

R Jalandra, AK Yadav, D Verma, N Dalal… - Biomedicine & …, 2020 - Elsevier
To develop diagnostics and detection methods, current research is focussed on targeting the
detection of coronavirus based on its RNA. Besides the RNA target, research reports are …

Electrochemical aptasensors based on the gold nanostructures

M Negahdary - Talanta, 2020 - Elsevier
Electrochemical aptasensors as novel diagnostic tools have attracted sufficient research
interest in biomedical sciences. In this review, recent leading trends about gold (Au) …

Aptamers targeting cardiac biomarkers as an analytical tool for the diagnostics of cardiovascular diseases: A review

N Komarova, O Panova, A Titov, A Kuznetsov - Biomedicines, 2022 - mdpi.com
The detection of cardiac biomarkers is used for diagnostics, prognostics, and the risk
assessment of cardiovascular diseases. The analysis of cardiac biomarkers is routinely …

Electrochemical immunosensor for determination of cardiac troponin I using two-dimensional metal-organic framework/Fe3O4–COOH nanosheet composites loaded …

A Ahmadi, SM Khoshfetrat, Z Mirzaeizadeh, S Kabiri… - Talanta, 2022 - Elsevier
Cardiac troponin-I (CTnI) is one of the most popular biomarkers which can be utilized for the
diagnosis and control of acute myocardial infarction in clinical practice. Here, a sandwich …

Nanomaterial-based aptasensors as an efficient substitute for cardiovascular disease diagnosis: Future of smart biosensors

A Azzouz, L Hejji, C Sonne, KH Kim, V Kumar - Biosensors and …, 2021 - Elsevier
As a major cause of deaths in developed countries, cardiovascular disease (CVD) has been
a big burden for human health systems. Its early and rapid detection is crucial to efficiently …

Acute myocardial infarction biosensor: a review from bottom up

JA Reyes-Retana, LC Duque-Ossa - Current problems in cardiology, 2021 - Elsevier
Acute myocardial infarction (AMI) is a cardiovascular disease that is produced due to a
deficiency of oxygen generating irreversible damage in the heart muscle. In diagnosis …

Cardiac biomarkers and detection methods for myocardial infarction

SY Kim, JP Lee, WR Shin, IH Oh, JY Ahn… - Molecular & Cellular …, 2022 - Springer
Background A significant heart attack known as a myocardial infarction (MI) occurs when the
blood supply to the heart is suddenly interrupted, harming the heart muscles due to a lack of …

Amperometric aptasensor with sandwich-type architecture for troponin I based on carboxyethylsilanetriol-modified graphene oxide coated electrodes

A Villalonga, I Estabiel, AM Pérez-Calabuig… - Biosensors and …, 2021 - Elsevier
A novel amperometric aptasensor for the specific detection of cardiac troponin I (cTnI) was
constructed by using screen-printed carbon electrodes coated with a carboxyethylsilanetriol …