Gold (III) complexes in medicinal chemistry
PI da Silva Maia, VM Deflon, U Abram - Future medicinal chemistry, 2014 - Taylor & Francis
A number of gold (III) compounds has been designed with the objective of overcoming the
disadvantages associated with the platinum-based drugs for cancer treatment. Compounds …
disadvantages associated with the platinum-based drugs for cancer treatment. Compounds …
Synthesis, characterization, and biological activity of some 2, 4-diketo esters containing dehydrozingerone fragment: DNA and protein binding study
K Mihajlović, N Joksimović, N Janković… - Bioorganic & Medicinal …, 2023 - Elsevier
Due to the increased resistance to antibiotics, in recent years there has been a growing
interest in the discovery of new antimicrobial agents from different sources. Bacteria that are …
interest in the discovery of new antimicrobial agents from different sources. Bacteria that are …
[HTML][HTML] Square planar Au (III), Pt (II) and Cu (II) complexes with quinoline-substituted 2, 2′: 6′, 2 ″-terpyridine ligands: From in vitro to in vivo biological properties
Cancer is the second leading cause of death worldwide. Cisplatin has challenged cancer
treatment; however, resistance and side effects hamper its use. New agents displaying …
treatment; however, resistance and side effects hamper its use. New agents displaying …
Spectroscopy, electrochemistry and antiproliferative properties of Au (iii), Pt (ii) and Cu (ii) complexes bearing modified 2, 2′: 6′, 2′′-terpyridine ligands
Structural, spectroscopic and electrochemical properties of six complexes [AuCl (L1)](PF6)
2· CH3CN (1),[AuCl (L2)](PF6) 2 (2),[PtCl (L1)](BPh4)· CH3CN (3),[PtCl (L2)](SO3CF3)(4) …
2· CH3CN (1),[AuCl (L2)](PF6) 2 (2),[PtCl (L1)](BPh4)· CH3CN (3),[PtCl (L2)](SO3CF3)(4) …
New gold pincer-type complexes: synthesis, characterization, DNA binding studies and cytotoxicity
S Radisavljević, I Bratsos, A Scheurer… - Dalton …, 2018 - pubs.rsc.org
With the aim of assessing whether Au (III) compounds with pincer type ligands might be
utilized as potential antitumor agents, three new monofunctional Au (III) complexes of the …
utilized as potential antitumor agents, three new monofunctional Au (III) complexes of the …
The synthesis, spectroscopic characterization and anticancer activity of new mono and binuclear phosphanegold (I) dithiocarbamate complexes
A new series of mononuclear [t-Bu3PAuS2CN (C7H7) 2](1), and binuclear [(DPPM) Au2
(S2CN (CH3) 2) 2](2),[(DPPM) Au2 (S2CN (C2H5) 2) 2](3) and [(DPPM) Au2 (S2CN (C7H7) …
(S2CN (CH3) 2) 2](2),[(DPPM) Au2 (S2CN (C2H5) 2) 2](3) and [(DPPM) Au2 (S2CN (C7H7) …
Anticancer activity and apoptosis induction of gold (III) complexes containing 2, 2′-bipyridine-3, 3′-dicarboxylic acid and dithiocarbamates
Three novel gold (III) complexes (1–3) of general composition [Au (Bipydc)(S2CNR2)] Cl2
(Bipydc= 2, 2′-bipyridine-3, 3′-dicarboxylic acid and R= methyl for …
(Bipydc= 2, 2′-bipyridine-3, 3′-dicarboxylic acid and R= methyl for …
Cytotoxic gold (iii) complexes incorporating a 2, 2′: 6′, 2′′-terpyridine ligand framework–the impact of the substituent in the 4′-position of a terpy ring
Two gold (III) complexes incorporating 2, 2′: 6′, 2′′-terpyridine derivatives have been
synthesised and characterized, and the possibility of tuning the cytotoxic activity by structural …
synthesised and characterized, and the possibility of tuning the cytotoxic activity by structural …
Impedance technology reveals correlations between cytotoxicity and lipophilicity of mono and bimetallic phosphine complexes
Label free impedance technology enables the monitoring of cell response patterns post
treatment with drugs or other chemicals. Using this technology, a correlation between the …
treatment with drugs or other chemicals. Using this technology, a correlation between the …
Synthesis, characterization and in vitro cytotoxicity of gold (III) dialkyl/diaryldithiocarbamato complexes
A series of six dialkyl/diaryldithiocarbamato (dtc) gold (III) complexes 1–6 of the composition
[Au (Me2dtc) 2] Cl (1),[Au (Me2dtc) Cl2](2),[Au (Et2dtc) 2] Cl (3),[Au (Et2dtc) Cl2](4),[Au …
[Au (Me2dtc) 2] Cl (1),[Au (Me2dtc) Cl2](2),[Au (Et2dtc) 2] Cl (3),[Au (Et2dtc) Cl2](4),[Au …