The aim of this International Menopause Society White Paper on premature ovarian
insufficiency (POI) is to provide the latest information regarding this distressing condition …

Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

Premature ovarian failure (POF) is a leading cause of women's infertility without effective
treatment. Here we show that intravenous injection of Ab4B19, an agonistic antibody for the …

Reproductive disorders, including intrauterine adhesion (IUA), premature ovarian
insufficiency (POI), and polycystic ovary syndrome (PCOS), are great threats to female …

Intraovarian platelet-rich plasma (PRP) infusion was recently introduced in the context of
addressing ovarian insufficiency. Reporting on its effectiveness prior to adopting in clinical …

The quality and maturation of an oocyte not only play decisive roles in fertilization and
embryo success, but also have long-term impacts on the later growth and development of …

STUDY QUESTION How do elastic matrisome components change during the lifetime of the
human ovary? SUMMARY ANSWER The deposition and remodeling of mechanical …

STUDY QUESTION What are the effects of cyclophosphamide exposure on the human ovary
and can anti-Mullerian hormone (AMH) and rapamycin protect against these? SUMMARY …

Rationale: Accumulated evidence indicates that environmental plasticizers are a threat to
human and animal fertility. Di (2-ethylhexyl) phthalate (DEHP), a plasticizer to which humans …

The mammalian ovary has two main functions—producing mature oocytes for fertilization
and secreting hormones for maintaining the ovarian endocrine functions. Both functions are …