Conspectus DNA G-quadruplex secondary structures formed in guanine-rich human
telomeres and oncogene promoters are functionally important and have emerged as a …

Guanine-rich DNA sequences have the propensity to adopt four-stranded tetrahelical G-
quadruplex (G4) structures that are overrepresented in gene promoters. The structural …

Over the past decade, nucleic acid chemists have seen the spectacular emergence of
molecules designed to interact efficiently and selectively with a peculiar DNA structure …

Thioflavin T (ThT) becomes fluorescent in the presence of the G-quadruplex structure such
as that formed by the human telomeric motif. In this report, we extend and generalize these …

Carbazole skeleton is the key structural motif of many biologically active compounds
including synthetic and natural products. Over the past several years, a large number of …

myc is a proto-oncogene that plays an important role in the promotion of cellular growth and
proliferation. Understanding the regulation of c-myc is important in cancer biology, as it is …

The telomeric G-rich single-stranded DNA can adopt in vitro an intramolecular quadruplex
structure, which has been shown to directly inhibit telomerase activity. The reactivation of …

Mounting evidence supports the presence of biologically relevant G‐quadruplexes in single‐
cell organisms, but the existence of endogenous G‐quadruplex structures in mammalian …

Aptamers are single stranded DNA or RNA molecules that have been selected using in vitro
techniques to bind target molecules with high affinity and selectivity, rivaling antibodies in …

Biosensing processes such as molecular beacons require non‐trivial effort to covalently
label or mark biomolecules. We report here a label‐free DNA assay system with a simple …