Advances in metal-induced oxidative stress and human disease

K Jomova, M Valko - Toxicology, 2011 - Elsevier
Detailed studies in the past two decades have shown that redox active metals like iron (Fe),
copper (Cu), chromium (Cr), cobalt (Co) and other metals undergo redox cycling reactions …

Metals, toxicity and oxidative stress

M Valko, H Morris, MTD Cronin - Current medicinal chemistry, 2005 - ingentaconnect.com
Metal-induced toxicity and carcinogenicity, with an emphasis on the generation and role of
reactive oxygen and nitrogen species, is reviewed. Metal-mediated formation of free radicals …

Urbanization, oxidative stress and inflammation: a question of evolving, acclimatizing or co** with urban environmental stress

C Isaksson - Functional Ecology, 2015 - Wiley Online Library
To estimate the impact of urbanization on wild animals, it is important to know how different
species, populations and/or individuals deal with and respond to environmental stress. Are …

Cadmium and cellular signaling cascades: interactions between cell death and survival pathways

F Thévenod, WK Lee - Archives of toxicology, 2013 - Springer
Cellular stress elicited by the toxic metal Cd 2+ does not coerce the cell into committing to
die from the onset. Rather, detoxification and adaptive processes are triggered concurrently …

Metals and apoptosis: recent developments

SVS Rana - Journal of trace elements in medicine and biology, 2008 - Elsevier
Apoptosis, also known as programmed cell death is a highly regulated and crucial process
found in all multicellular organisms. It is not only implicated in regulatory mechanisms of …

Cadmium and cellular signaling cascades: to be or not to be?

F Thévenod - Toxicology and applied pharmacology, 2009 - Elsevier
The cellular effects of the toxic metal cadmium (Cd) are manifold. A large proportion of the
cellular reactions affected by ionic Cd2+ are mediated by cellular signaling cascades. The …

Orthopaedic metals and their potential toxicity in the arthroplasty patient: a review of current knowledge and future strategies

GM Keegan, ID Learmonth… - The Journal of Bone & …, 2007 - boneandjoint.org.uk
The long-term effects of metal-on-metal arthroplasty are currently under scrutiny because of
the potential biological effects of metal wear debris. This review summarises data describing …

Metal-related oxidative stress in birds

MJ Koivula, T Eeva - Environmental pollution, 2010 - Elsevier
Metals can cause oxidative stress by increasing the formation of reactive oxygen species
(ROS), which render antioxidants incapable of defence against growing amounts of free …

Cadmium chloride induces DNA damage and apoptosis of human liver carcinoma cells via oxidative stress

A Skipper, JN Sims, CG Yedjou… - International journal of …, 2016 - mdpi.com
Cadmium is a heavy metal that has been shown to cause its toxicity in humans and animals.
Many documented studies have shown that cadmium produces various genotoxic effects …

Low dose of arsenic trioxide triggers oxidative stress in zebrafish brain: expression of antioxidant genes

S Sarkar, S Mukherjee, A Chattopadhyay… - Ecotoxicology and …, 2014 - Elsevier
Occurrence of arsenic in the aquatic environment of West Bengal (India), Bangladesh and
other countries are of immediate environmental concern. In the present study, zebrafish …