Mass spectrometry imaging: a review of emerging advancements and future insights

AR Buchberger, K DeLaney, J Johnson… - Analytical …, 2017 - pmc.ncbi.nlm.nih.gov
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations
into the spatial distribution of molecular species in a variety of samples. It has the capability …

Unsupervised machine learning for exploratory data analysis in imaging mass spectrometry

N Verbeeck, RM Caprioli… - Mass spectrometry …, 2020 - Wiley Online Library
Imaging mass spectrometry (IMS) is a rapidly advancing molecular imaging modality that
can map the spatial distribution of molecules with high chemical specificity. IMS does not …

Spatial metabolomics of in situ host–microbe interactions at the micrometre scale

B Geier, EM Sogin, D Michellod, M Janda… - Nature …, 2020 - nature.com
Spatial metabolomics describes the location and chemistry of small molecules involved in
metabolic phenotypes, defence molecules and chemical interactions in natural communities …

MALDI-MSI towards multimodal imaging: challenges and perspectives

M Tuck, F Grélard, L Blanc, N Desbenoit - Frontiers in Chemistry, 2022 - frontiersin.org
Multimodal imaging is a powerful strategy for combining information from multiple images. It
involves several fields in the acquisition, processing and interpretation of images. As …

Mass spectrometry imaging and integration with other imaging modalities for greater molecular understanding of biological tissues

T Porta Siegel, G Hamm, J Bunch, J Cappell… - Molecular imaging and …, 2018 - Springer
Over the last two decades, mass spectrometry imaging (MSI) has been increasingly
employed to investigate the spatial distribution of a wide variety of molecules in complex …

Mass spectrometry imaging for clinical research–latest developments, applications, and current limitations

PM Vaysse, RMA Heeren, T Porta, B Balluff - Analyst, 2017 - pubs.rsc.org
Mass spectrometry is being used in many clinical research areas ranging from toxicology to
personalized medicine. Of all the mass spectrometry techniques, mass spectrometry …

Emerging computational methods in mass spectrometry imaging

H Hu, J Laskin - Advanced Science, 2022 - Wiley Online Library
Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …

Recent developments in machine learning for mass spectrometry

AG Beck, M Muhoberac, CE Randolph… - ACS Measurement …, 2024 - ACS Publications
Statistical analysis and modeling of mass spectrometry (MS) data have a long and rich
history with several modern MS-based applications using statistical and chemometric …

Multimodal imaging mass spectrometry: next generation molecular map** in biology and medicine

EK Neumann, KV Djambazova… - Journal of the …, 2020 - ACS Publications
Imaging mass spectrometry has become a mature molecular map** technology that is
used for molecular discovery in many medical and biological systems. While powerful by …

Cellular resolution in clinical MALDI mass spectrometry imaging: the latest advancements and current challenges

K Ščupáková, B Balluff, C Tressler… - Clinical Chemistry and …, 2020 - degruyter.com
Mass spectrometry (MS) is the workhorse of metabolomics, proteomics and lipidomics. Mass
spectrometry imaging (MSI), its extension to spatially resolved analysis of tissues, is a …