Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

RNA-based therapy is a promising and potential strategy for disease treatment by
introducing exogenous nucleic acids such as messenger RNA (mRNA), small interfering …

Ionizable lipid nanoparticles (LNPs) have been widely used for in vivo delivery of RNA
therapeutics into the liver. However, a main challenge remains to develop LNP formulations …

The RNA interference (RNAi) pathway possesses immense potential in silencing any gene
in human cells. Small interfering RNA (siRNA) can efficiently trigger RNAi silencing of …

Controlled drug delivery formulations have revolutionized treatments for a range of health
conditions. Over decades of innovation, layer-by-layer (LbL) self-assembly has emerged as …

Cancer often develops multidrug resistance (MDR) when cancer cells become resistant to
numerous structurally and functionally different chemotherapeutic agents. MDR is …

Abstract Hypothesis Dynamic Light Scattering (DLS) generated particle size distributions
(PSD) of polymer-stabilized nanoparticles are dependent on the optimization parameters …

Polymeric vehicles are versatile tools for therapeutic gene delivery. Many polymers—when
assembled with nucleic acids into vehicles—can protect the cargo from degradation and …