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Half-sandwich Ru (II) N-heterocyclic carbene complexes in anticancer drug design
OAL Rojas, S Cordeiro, PV Baptista… - Journal of Inorganic …, 2023 - Elsevier
The ruthenium arene fragment is a rich source for the design of anticancer drugs; in this
design, the co-ligand is a critical factor for obtaining effective anticancer complexes. In …
design, the co-ligand is a critical factor for obtaining effective anticancer complexes. In …
Novel 1, 3‐diphenyl‐4‐(N, N‐dimethylimido dicarbonimidic diamide azo)‐5‐pyrazolone and its chelates with manganese, nickel, copper, and zinc divalent metal ions …
OA Abbas, OM El‐Roudi… - Applied Organometallic …, 2023 - Wiley Online Library
A novel 1, 3‐diphenyl‐4‐(N, N‐dimethylimidodicarbonimidic diamide azo)‐5‐pyrazolone as
a ligand, simplified as DNP, and its chelates were prepared. Characterization of the …
a ligand, simplified as DNP, and its chelates were prepared. Characterization of the …
Biological activities of ruthenium NHC complexes: An update
A Catalano, A Mariconda, MS Sinicropi, J Ceramella… - Antibiotics, 2023 - mdpi.com
Ruthenium N-heterocyclic carbene (NHC) complexes have unique physico-chemical
properties as catalysts and a huge potential in medicinal chemistry and pharmacology …
properties as catalysts and a huge potential in medicinal chemistry and pharmacology …
Sythesis, characterisation, anticancer and antimicrobial activity of Ag-N-heterocyclic carbene complexes containing benzimidazole derivatives
To prepare a novel series of silver (I) complexes, the interaction of benzimidazolium salts
having their two nitrogen atoms substituted by bulky groups with Ag 2 O in DCM has been …
having their two nitrogen atoms substituted by bulky groups with Ag 2 O in DCM has been …
Synthesis, characterization, DNA interaction and anti-bacterial studies of Cu (ii), Co (ii) and Ni (ii) metal complexes containing azo-dye ligand
BR Kirthan, MC Prabhakara, HSB Naik… - Chemical Data …, 2020 - Elsevier
The derivatives of the pyrazole and its metal complexes are considered a pharmacologically
important active frame that possesses that some types of pharmacological activities. From …
important active frame that possesses that some types of pharmacological activities. From …
Organometallic dendrimers based on Ruthenium (II) N-heterocyclic carbenes and their implication as delivery systems of anticancer small interfering RNA
T Rodriguez-Prieto, S Michlewska, M Hołota… - Journal of inorganic …, 2021 - Elsevier
With the purpose of obtaining a new dendritic system against cancer, this paper is focused
on the synthesis of spherical carbosilane metallodendrimers of different generations holding …
on the synthesis of spherical carbosilane metallodendrimers of different generations holding …
Plausible PEPPSI catalysts for direct C–H functionalization of five-membered heterocyclic bioactive motifs: synthesis, spectral, X-ray crystallographic characterizations …
In this study, a series of benzimidazolium salts were synthesized as asymmetric N-
heterocyclic carbene (NHC) precursors. Nine novel palladium complexes with the general …
heterocyclic carbene (NHC) precursors. Nine novel palladium complexes with the general …
Substituted N-heterocyclic carbene PEPPSI-type palladium complexes with different N-coordinated ligands: Involvement in the direct CH bond activation of …
In this study new benzimidazolium salt as N-heterocyclic carbene precursors and their
related new PEPPSI-Pd (II)–N-heterocyclic carbene (NHC) complexes 3a-e were prepared …
related new PEPPSI-Pd (II)–N-heterocyclic carbene (NHC) complexes 3a-e were prepared …
The small molecules targeted therapies of endometrial cancer: Progress, challenges, and opportunities
F Yang, T Zhao, S Milaneh, C Zhang, DJ **ang… - RSC Medicinal …, 2024 - pubs.rsc.org
Endometrial cancer (EC) is a common malignancy among women worldwide, and its
recurrence makes it a common cause of cancer-related death. Surgery and external …
recurrence makes it a common cause of cancer-related death. Surgery and external …
Anticancer, antimicrobial and antiparasitical activities of copper(I) complexes based on N-heterocyclic carbene (NHC) ligands bearing aryl substituents
New benzimidazolium salts were synthesized as N-heterocyclic carbene precursors. These
NHC precursors were metallated with Cu2O and CuI in acetone and water under reflux to …
NHC precursors were metallated with Cu2O and CuI in acetone and water under reflux to …