Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions
R Bouillon, C Marcocci, G Carmeliet, D Bikle… - Endocrine …, 2019 - academic.oup.com
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
Exploring vitamin D metabolism and function in cancer
Vitamin D, traditionally known as an essential nutrient, is a precursor of a potent steroid
hormone that regulates a broad spectrum of physiological processes. In addition to its …
hormone that regulates a broad spectrum of physiological processes. In addition to its …
Vitamin D: metabolism, molecular mechanism of action, and pleiotropic effects
1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …
The role of vitamin D in reducing cancer risk and progression
D Feldman, AV Krishnan, S Swami… - Nature reviews …, 2014 - nature.com
Vitamin D is not really a vitamin but the precursor to the potent steroid hormone calcitriol,
which has widespread actions throughout the body. Calcitriol regulates numerous cellular …
which has widespread actions throughout the body. Calcitriol regulates numerous cellular …
The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …
level. First, the interactions between curcumin and its molecular targets are addressed on …
Cytochrome P450-mediated metabolism of vitamin D
The vitamin D signal transduction system involves a series of cytochrome P450-containing
sterol hydroxylases to generate and degrade the active hormone, 1α, 25-dihydroxyvitamin D …
sterol hydroxylases to generate and degrade the active hormone, 1α, 25-dihydroxyvitamin D …
Vitamin D and human health: lessons from vitamin D receptor null mice
R Bouillon, G Carmeliet, L Verlinden… - Endocrine …, 2008 - academic.oup.com
The vitamin D endocrine system is essential for calcium and bone homeostasis. The precise
mode of action and the full spectrum of activities of the vitamin D hormone, 1, 25 …
mode of action and the full spectrum of activities of the vitamin D hormone, 1, 25 …
25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D
CYP24A1 is the cytochrome P450 component of the 25-hydroxyvitamin D3-24-hydroxylase
enzyme that catalyzes the conversion of 25-hydroxyvitamin D3 (25-OH-D3) and 1, 25 …
enzyme that catalyzes the conversion of 25-hydroxyvitamin D3 (25-OH-D3) and 1, 25 …
World Health Organization classification of tumours: Pathology & genetics of tumours of the urinary system and male genital organs
TY Chan - Urology, 2005 - goldjournal.net
This 2004 volume in the World Health Organization series on histologic and genetic ty**
of human tumors covers tumors of the kidney, urinary system, prostate, testis and …
of human tumors covers tumors of the kidney, urinary system, prostate, testis and …
The anti-inflammatory effects of vitamin D in tumorigenesis
W Liu, L Zhang, HJ Xu, Y Li, CM Hu, JY Yang… - International journal of …, 2018 - mdpi.com
In conjunction with the classical functions of regulating intestinal, bone, and kidney calcium
and phosphorus absorption, as well as bone mineralization of vitamin D, the population …
and phosphorus absorption, as well as bone mineralization of vitamin D, the population …