Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Celastrol, triptolide and triptonide are the most significant active ingredients of Tripterygium
wilfordii Hook F (TWHF). In 2007, the 'Cell'journal ranked celastrol, triptolide, artemisinin …

Kidneys are one of the targets for SARS-CoV-2, it is reported that up to 36% of patients with
SARS-CoV-2 infection would develop into acute kidney injury (AKI). AKI is associated with …

Matrine is an alkaloid isolated from the traditional Chinese medicine Sophora flavescens
Aiton. At present, a large number of studies have proved that matrine has an anticancer …

Ethnopharmacological relevance “Dogel ebs” was known as Sophora flavescens Ait., which
has been widely utilized in the clinical practice of traditional Chinese Mongolian herbal …

Drug resistance is still an obstacle in cancer therapy, leading to the failure of tumor
treatment. The emergence of tumor drug resistance has always been a main concern of …

Drug repurposing (or repositioning) is an emerging concept to use old drugs for new
treatment indications. Phytochemicals isolated from medicinal plants have been largely …

Abstract The plant Sophora flavescens Ait. has been used in the clinical management of
colorectal cancer (CRC). Its constituent compounds, notably the alkaloids matrine …

The main goal of this work was to screen the antiproliferative activity and mechanism of
actions of two copper complexes:[Cu (dmp) 2 (CH 3 CN)] 2+(1) and [Cu (phen) 2 (CH 3 CN)] …

Patients with breast cancer and breast cancer survivors are frequent users of botanicals and
their bioactive phytochemicals. In China, active ingredients in Sophora flavescens like …