Alzheimer's disease: updated multi-targets therapeutics are in clinical and in progress
Z Sang, K Wang, J Dong, L Tang - European journal of medicinal chemistry, 2022 - Elsevier
Alzheimer's disease is a chronic and progressive brain neurodegenerative disease affecting
over 30 million people globally. Currently, no effective treatment is available due to multiple …
over 30 million people globally. Currently, no effective treatment is available due to multiple …
Drugs in clinical trials for Alzheimer's disease: the major trends
SO Bachurin, EV Bovina… - Medicinal research …, 2017 - Wiley Online Library
Alzheimer's disease (AD) is characterized by a chronic and progressive neurodegenerative
process resulting from the intracellular and extracellular accumulation of fibrillary proteins …
process resulting from the intracellular and extracellular accumulation of fibrillary proteins …
Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …
characterized by two core behavioral symptoms, namely impairments in social …
Therapeutics of neurotransmitters in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by the
loss of memory, multiple cognitive impairments and changes in the personality and …
loss of memory, multiple cognitive impairments and changes in the personality and …
Treatment of ADHD: Drugs, psychological therapies, devices, complementary and alternative methods as well as the trends in clinical trials
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common
neurodevelopmental disorders having a high influence on social interactions. The number of …
neurodevelopmental disorders having a high influence on social interactions. The number of …
Role of neuroinflammation in autism spectrum disorder and the emergence of brain histaminergic system. Lessons also for BPSD?
Many behavioral and psychological symptoms of dementia (BPSD) share similarities in
executive functioning and communication deficits with those described in several …
executive functioning and communication deficits with those described in several …
Histamine release from mast cells and basophils
Mast cells and basophils represent the most relevant source of histamine in the immune
system. Histamine is stored in cytoplasmic granules along with other amines (eg, serotonin) …
system. Histamine is stored in cytoplasmic granules along with other amines (eg, serotonin) …
Mast cell activation: beyond histamine and tryptase
TC Theoharides, AI Perlman, A Twahir… - Expert Review of …, 2023 - Taylor & Francis
Introduction Mast cells are found in all tissues and express numerous surface receptors
allowing them to sense and respond to allergic, autoimmune, environmental …
allowing them to sense and respond to allergic, autoimmune, environmental …
Cognitive deficit in schizophrenia: from etiology to novel treatments
AL Martínez, J Brea, S Rico, MT De los Frailes… - International journal of …, 2021 - mdpi.com
Schizophrenia is a major mental illness characterized by positive and negative symptoms,
and by cognitive deficit. Although cognitive impairment is disabling for patients, it has been …
and by cognitive deficit. Although cognitive impairment is disabling for patients, it has been …
Mast cells in the autonomic nervous system and potential role in disorders with dysautonomia and neuroinflammation
Mast cells (MC) are ubiquitous in the body, and they are critical for not only in allergic
diseases but also in immunity and inflammation, including having potential involvement in …
diseases but also in immunity and inflammation, including having potential involvement in …