Osteoporosis has been defined as the silent disease of the 21st century, becoming a public
health risk due to its severity, chronicity and progression and affecting mainly …

Bone remodeling is a continuous process that maintains the homeostasis of the skeletal
system, and it depends on the homeostasis between bone-forming osteoblasts and bone …

Implantation of stem cells for tissue regeneration faces significant challenges such as
immune rejection and teratoma formation. Cell‐free tissue regeneration thus has a potential …

Bone defects are commonly caused by severe trauma, malignant tumors, or congenital
diseases and remain among the toughest clinical problems faced by orthopedic surgeons …

Human mesenchymal stem cells (MSCs) have become a hot topic in the development of cell
therapies and bioengineering. All kinds of MSCs are genomic stable and have the self …

Recovery from bone, osteochondral, and cartilage injuries/diseases has been burdensome
owing to the damaged vasculature of large defects and/or avascular nature of cartilage …

Abstract 3D-printed composite scaffolds have emerged as an alternative to deal with existing
limitations when facing bone reconstruction. The aim of the study was to systematically …

Mitogen‐activated protein kinase (MAPK) signaling pathways organize a great constitution
network that regulates several physiological processes, like cell growth, differentiation, and …

Osteonecrosis of the femoral head (ONFH) is a devastating and complicated disease with an
unclear etiology. Femoral head‐preserving surgeries have been devoted to delaying and …

Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …