The NF-κB family of transcription factors has an essential role in inflammation and innate
immunity. Furthermore, NF-κB is increasingly recognized as a crucial player in many steps of …

The transcription factor NF-κB has been the focus of intense investigation for nearly two
decades. Over this period, considerable progress has been made in determining the …

Nuclear factor-κB (NF-κB) transcription factors and the signalling pathways that activate
them are central coordinators of innate and adaptive immune responses. More recently, it …

Nuclear factor-κB (NF-κB) is a transcription factor that has crucial roles in inflammation,
immunity, cell proliferation and apoptosis. Activation of NF-κB mainly occurs via IκB kinase …

Apoptosis plays an important role in development and maintenance of tissue homeostasis.
Intensive efforts have been made to explore the molecular mechanisms of the apoptotic …

In response to environmental stresses, a family of protein kinases phosphorylate eIF2
(eukaryotic initiation factor 2) to alleviate cellular injury or alternatively induce apoptosis …

It is only recently that the full importance of nuclear factor-κB (NF-κB) signalling to cancer
development has been understood. Although much attention has focused on the upstream …

Several recent studies have identified nuclear factor-κB as a key modulator in driving
inflammation to cancers. Besides this transcription factor, essential in regulating …

Because nuclear factor-κB (NF-κB) is a ubiquitously expressed proinflammatory transcription
factor that regulates the expression of over 500 genes involved in cellular transformation …

Nuclear factor-κB (NF-κB) is a major transcription factor that plays an essential role in
several aspects of human health including the development of innate and adaptive …