An updated review of chemical compounds with anti-Toxoplasma gondii activity
The opportunistic apicomplexan parasite Toxoplasma gondii is the etiologic agent for
toxoplasmosis, which can infect a widespread range of hosts, particularly humans and warm …
toxoplasmosis, which can infect a widespread range of hosts, particularly humans and warm …
Metabolic changes in Toxoplasma gondii-infected host cells measured by autofluorescence imaging
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular
parasite that infects warm-blooded vertebrates across the world. In humans, seropositivity …
parasite that infects warm-blooded vertebrates across the world. In humans, seropositivity …
Functional and biochemical characterization of the Toxoplasma gondii succinate dehydrogenase complex
MF Silva, K Douglas, S Sandalli, AE Maclean… - PLoS …, 2023 - journals.plos.org
The mitochondrial electron transport chain (mETC) is a series of membrane embedded
enzymatic complexes critical for energy conversion and mitochondrial metabolism. In …
enzymatic complexes critical for energy conversion and mitochondrial metabolism. In …
The Toxoplasma gondii mitochondrial transporter ABCB7L is essential for the biogenesis of cytosolic and nuclear iron-sulfur cluster proteins and cytosolic translation
ABSTRACT Iron-sulfur (Fe-S) clusters are ubiquitous inorganic cofactors required for
numerous essential cellular pathways. Since they cannot be scavenged from the …
numerous essential cellular pathways. Since they cannot be scavenged from the …
A patatin-like phospholipase is important for mitochondrial function in malaria parasites
Plasmodium parasites rely on a functional electron transport chain (ETC) within their
mitochondrion for proliferation, and compounds targeting mitochondrial functions are …
mitochondrion for proliferation, and compounds targeting mitochondrial functions are …
A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites
Apicomplexans are widespread parasites of humans and other animals, and include the
causative agents of malaria (Plasmodium species) and toxoplasmosis (Toxoplasma gondii) …
causative agents of malaria (Plasmodium species) and toxoplasmosis (Toxoplasma gondii) …
An essential role for an Fe-S cluster protein in the cytochrome c oxidase complex of Toxoplasma parasites
The mitochondrial electron transport chain (ETC) of apicomplexan parasites differs
considerably from the ETC of the animals that these parasites infect, and is the target of …
considerably from the ETC of the animals that these parasites infect, and is the target of …
Two ancient membrane pores mediate mitochondrial-nucleus membrane contact sites
J Ovciarikova, S Shikha, A Lacombe, F Courjol… - Journal of Cell …, 2024 - rupress.org
Coordination between nucleus and mitochondria is essential for cell survival, and thus
numerous communication routes have been established between these two organelles over …
numerous communication routes have been established between these two organelles over …
A myzozoan-specific protein is an essential membrane-anchoring component of the succinate dehydrogenase complex in Toxoplasma parasites
SM Zwahlen, JA Hayward, CS Maguire… - Open …, 2024 - royalsocietypublishing.org
Succinate dehydrogenase (SDH) is a protein complex that functions in the tricarboxylic acid
cycle and the electron transport chain of mitochondria. In most eukaryotes, SDH is highly …
cycle and the electron transport chain of mitochondria. In most eukaryotes, SDH is highly …
[HTML][HTML] Metabolic changes to host cells with Toxoplasma gondii infection
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular
parasite that infects warm-blooded vertebrates across the world. In humans, seropositivity …
parasite that infects warm-blooded vertebrates across the world. In humans, seropositivity …