Sex differences in type 2 diabetes

A Kautzky-Willer, M Leutner, J Harreiter - Diabetologia, 2023‏ - Springer
The prevalence of type 2 diabetes mellitus is increasing in both sexes, but men are usually
diagnosed at a younger age and lower body fat mass than women. Worldwide, an estimated …

2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on …

PA Heidenreich, B Bozkurt, D Aguilar, LA Allen… - Journal of the American …, 2022‏ - jacc.org
Abstract Aim The “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure”
replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the …

2023 ACC expert consensus decision pathway on management of heart failure with preserved ejection fraction: a report of the American College of Cardiology …

MM Kittleson, GS Panjrath, K Amancherla… - Journal of the American …, 2023‏ - jacc.org
The American College of Cardiology (ACC) has a long history of develo** documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …

Gender medicine: effects of sex and gender on cardiovascular disease manifestation and outcomes

V Regitz-Zagrosek, C Gebhard - Nature Reviews Cardiology, 2023‏ - nature.com
Despite a growing body of evidence, the distinct contributions of biological sex and the
sociocultural dimension of gender to the manifestations and outcomes of ischaemic heart …

2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice …

FLJ Visseren, F Mach, YM Smulders… - European heart …, 2021‏ - academic.oup.com
Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030

B Vogel, M Acevedo, Y Appelman, CNB Merz… - The Lancet, 2021‏ - thelancet.com
Cardiovascular disease is the leading cause of death in women. Decades of grassroots
campaigns have helped to raise awareness about the impact of cardiovascular disease in …

Impact of sex and gender on COVID-19 outcomes in Europe

C Gebhard, V Regitz-Zagrosek, HK Neuhauser… - Biology of sex …, 2020‏ - Springer
Abstract Background Emerging evidence from China suggests that coronavirus disease
2019 (COVID-19) is deadlier for infected men than women with a 2.8% fatality rate being …

Effect of empagliflozin in patients with heart failure across the spectrum of left ventricular ejection fraction

J Butler, M Packer, G Filippatos, JP Ferreira… - European heart …, 2022‏ - academic.oup.com
Aims No therapy has shown to reduce the risk of hospitalization for heart failure across the
entire range of ejection fractions seen in clinical practice. We assessed the influence of …

Patient phenotype profiling in heart failure with preserved ejection fraction to guide therapeutic decision making. A scientific statement of the Heart Failure Association …

SD Anker, MS Usman, MS Anker… - European Journal of …, 2023‏ - Wiley Online Library
Heart failure with preserved ejection fraction (HFpEF) represents a highly heterogeneous
clinical syndrome affected in its development and progression by many comorbidities. The …

From systemic inflammation to myocardial fibrosis: the heart failure with preserved ejection fraction paradigm revisited

WJ Paulus, MR Zile - Circulation research, 2021‏ - ahajournals.org
In accordance with the comorbidity-inflammation paradigm, comorbidities and especially
metabolic comorbidities are presumed to drive development and severity of heart failure with …