Liquid biopsy on the horizon in immunotherapy of non-small cell lung cancer: current status, challenges, and perspectives

Y Yang, H Liu, Y Chen, N ** in clinical practice
C Aggarwal, CD Rolfo, GR Oxnard, JE Gray… - Nature Reviews …, 2021 - nature.com
Upfront tumour genoty** is now considered an essential step in guiding treatment
decision-making in the management of patients with advanced-stage non-small-cell lung …

The role of liquid biopsy in early diagnosis of lung cancer

C Freitas, C Sousa, F Machado, M Serino… - Frontiers in …, 2021 - frontiersin.org
Liquid biopsy is an emerging technology with a potential role in the screening and early
detection of lung cancer. Several liquid biopsy-derived biomarkers have been identified and …

Circulating tumor cells in diagnosis and treatment of lung cancer

V Maly, O Maly, K Kolostova, V Bobek - In Vivo, 2019 - iv.iiarjournals.org
Circulating tumor cells (CTCs), detached from the primary tumor or metastases and shed in
the patient's bloodstream, represent a relatively easily obtainable sample of the cancer …

Patient-derived cell line, xenograft and organoid models in lung cancer therapy

KG Huo, E D'Arcangelo… - Translational lung cancer …, 2020 - pmc.ncbi.nlm.nih.gov
Lung cancer accounts for most cancer-related deaths worldwide and has an overall 5-year
survival rate of~ 15%. Cell lines have played important roles in the study of cancer biology …

Early diagnosis of lung cancer: which is the optimal choice?

J Ning, T Ge, M Jiang, K Jia, L Wang, W Li… - Aging (Albany …, 2021 - pmc.ncbi.nlm.nih.gov
The prognosis of lung cancer patients with different clinical stages is significantly different.
The 5-year survival of stage IA groups can exceed 90%, while patients with stage IV can be …

Liquid biopsies in lung cancer

M Kemper, C Krekeler, K Menck, G Lenz, G Evers… - Cancers, 2023 - mdpi.com
As lung cancer has the highest cancer-specific mortality rates worldwide, there is an urgent
need for new therapeutic and diagnostic approaches to detect early-stage tumors and to …

High-throughput label-free isolation of heterogeneous circulating tumor cells and CTC clusters from non-small-cell lung cancer patients

M Zeinali, M Lee, A Nadhan, A Mathur, C Hedman… - Cancers, 2020 - mdpi.com
(1) Background: Circulating tumor cell (CTC) clusters are emerging as clinically significant
harbingers of metastases in solid organ cancers. Prior to engaging these CTC clusters in …