Platelets are inflammatory anuclear cells with a well-established role in the development
and manifestation of atherosclerosis. Activated platelets secrete a plethora of chemokines …

The development and progression of cardiovascular disease (CVD) can mainly be attributed
to the narrowing of blood vessels caused by atherosclerosis and thrombosis, which induces …

Pulmonary thrombosis is a significant cause of patient mortality; however, there are no
effective in vitro models of thrombi formation in human lung microvessels that could also …

Traditionally, in vitro flow chamber experiments and in vivo arterial thrombosis studies have
been proved to be of vital importance to elucidate the mechanisms of platelet thrombus …

Blood platelets are anucleated circulating cells that play a critical role in hemostasis and are
also implicated in arterial thrombosis, a major cause of death worldwide. The biological …

While platelets have long been known to be essential for maintaining hemostasis in the
vasculature, their role in tissue repair, inflammation and innate and adaptive immunity is a …

Objective—Atherothrombosis is the main cause of myocardial infarction and ischemic stroke.
Although the extrinsic (tissue factor–factor VIIa [FVIIa]) pathway is considered as a major …

Introduction: Over the past 15 years, a wide range of agents have been developed for use in
surgical procedures to achieve hemostasis. These agents can be divided into three broad …

This paper addresses a significant paradox in biomaterials science; biocompatibility
phenomena have been experienced and described for over 50 years but without an agreed …

There is now good evidence that cytokines and growth factors are key factors in tissue repair
and often exert anti-infective activities. However, engineering such factors for global use …