Formation and integration of new neurons in the adult hippocampus

A Denoth-Lippuner, S Jessberger - Nature Reviews Neuroscience, 2021 - nature.com
Neural stem cells (NSCs) generate new neurons throughout life in the mammalian brain.
Adult-born neurons shape brain function, and endogenous NSCs could potentially be …

The role of adult hippocampal neurogenesis in brain health and disease

T Toda, SL Parylak, SB Linker, FH Gage - Molecular psychiatry, 2019 - nature.com
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …

GABAA receptors: structure, function, pharmacology, and related disorders

A Ghit, D Assal, AS Al-Shami, DEE Hussein - Journal of Genetic …, 2021 - Springer
Background γ-Aminobutyric acid sub-type A receptors (GABAARs) are the most prominent
inhibitory neurotransmitter receptors in the CNS. They are a family of ligand-gated ion …

Temporal control of mammalian cortical neurogenesis by m6A methylation

KJ Yoon, FR Ringeling, C Vissers, F Jacob, M Pokrass… - Cell, 2017 - cell.com
Summary N 6-methyladenosine (m 6 A), installed by the Mettl3/Mettl14 methyltransferase
complex, is the most prevalent internal mRNA modification. Whether m 6 A regulates …

[HTML][HTML] Adult neurogenesis in the hippocampus: from stem cells to behavior

JT Gonçalves, ST Schafer, FH Gage - Cell, 2016 - cell.com
The dentate gyrus of the mammalian hippocampus continuously generates new neurons
during adulthood. These adult-born neurons become functionally active and are thought to …

Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain

MP Jurkowski, L Bettio, E K. Woo, A Patten… - Frontiers in cellular …, 2020 - frontiersin.org
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Neurogenesis in the adult hippocampus

G Kempermann, H Song… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the
most attention, because it is involved in higher cognitive function, most notably memory …

Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior

YD Li, YJ Luo, ZK Chen, L Quintanilla, Y Cherasse… - Nature …, 2022 - nature.com
Adult hippocampal neurogenesis plays a critical role in memory and emotion processing,
and this process is dynamically regulated by neural circuit activity. However, it remains …

Lasting impact of general anaesthesia on the brain: mechanisms and relevance

L Vutskits, Z **e - Nature Reviews Neuroscience, 2016 - nature.com
General anaesthesia is usually considered to safely induce a reversible brain state allowing
the performance of surgery under optimal conditions. An increasing number of clinical and …

Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons

N Habib, Y Li, M Heidenreich, L Swiech… - Science, 2016 - science.org
Single-cell RNA sequencing (RNA-Seq) provides rich information about cell types and
states. However, it is difficult to capture rare dynamic processes, such as adult …