A review of particle shape effects on material properties for various engineering applications: from macro to nanoscale

U Ulusoy - Minerals, 2023 - mdpi.com
It is well known that most particle technology studies attempting to predict secondary
properties based on primary properties such as size and shape begin with particle …

Drug metabolites and their effects on the development of adverse reactions: Revisiting Lipinski's Rule of Five

CM Chagas, S Moss, L Alisaraie - International journal of pharmaceutics, 2018 - Elsevier
Many studies have shown that toxicities of anticancer drugs and their adverse effects are
related to their chemical structure and high molecular weight that may result in a number of …

The effect of particle shape on cellular interaction and drug delivery applications of micro-and nanoparticles

AB **dal - International journal of pharmaceutics, 2017 - Elsevier
Encapsulation of therapeutic agents in nanoparticles offers several benefits including
improved bioavailability, site specific delivery, reduced toxicity and in vivo stability of …

Chitosan/o-carboxymethyl chitosan nanoparticles for efficient and safe oral anticancer drug delivery: In vitro and in vivo evaluation

C Feng, Z Wang, C Jiang, M Kong, X Zhou, Y Li… - International journal of …, 2013 - Elsevier
The present study investigated the ability of a polyelectrolyte complex (CS/CMCS-NPs),
composed of chitosan (CS) and o-carboxymeymethy chitosan (CMCS) as a pH responsive …

Cyclodextrins-modified metallic nanoparticles for effective cancer therapy

S Gandhi, P Shende - Journal of Controlled Release, 2021 - Elsevier
Cancer, a disease of unknown origin is the second most common reason of death worldwide
after heart attacks and therefore is a major threat to human beings. Currently, chemotherapy …

Oral delivery of doxorubicin using novel polyelectrolyte-stabilized liposomes (layersomes)

S Jain, SR Patil, NK Swarnakar… - Molecular …, 2012 - ACS Publications
The present study explores the potential of polyelectrolyte-coated liposomes for improving
the oral deliverability of doxorubicin (Dox). As a part of formulation strategy, stearyl amine …

Lactoferrin/phenylboronic acid-functionalized hyaluronic acid nanogels loading doxorubicin hydrochloride for targeting glioma

M Zhang, S Asghar, C Tian, Z Hu, Q **, Z Chen… - Carbohydrate …, 2021 - Elsevier
Abstract Herein, lactoferrin (Lf)/phenylboronic acid (PBA)-functionalized hyaluronic acid
nanogels crosslinked with disulfide-bond crosslinker was developed as a reduction …

Dual cancer targeting using estrogen functionalized chitosan nanoparticles loaded with doxorubicin-estrone conjugate: A quality by design approach

BD Kurmi, R Paliwal, SR Paliwal - International journal of biological …, 2020 - Elsevier
In this study, estrone was used as targeting functionality in chitosan nanoparticles (DoxEs-
CSEsNPs) carrying doxorubicin-estrone conjugate for dual targeted intracellular delivery to …

Formulation and optimization of itraconazole polymeric lipid hybrid nanoparticles (Lipomer) using box behnken design

B Gajra, C Dalwadi, R Patel - DARU Journal of Pharmaceutical Sciences, 2015 - Springer
Background The objective of the study was to formulate and to investigate the combined
influence of 3 independent variables in the optimization of Polymeric lipid hybrid …

Immobilization of coacervate microcapsules in multilayer sodium alginate beads for efficient oral anticancer drug delivery

C Feng, R Song, G Sun, M Kong, Z Bao, Y Li… - …, 2014 - ACS Publications
We have designed and evaluated coacervate microcapsules-immobilized multilayer sodium
alginate beads (CMs-M-ALG-Beads) for oral drug delivery. The CMs-M-ALG-Beads were …