Drug-resistant tuberculosis: a persistent global health concern

M Farhat, H Cox, M Ghanem, CM Denkinger… - Nature Reviews …, 2024 - nature.com
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-
attributable deaths worldwide and is driven by both ongoing resistance acquisition and …

Therapeutic developments for tuberculosis and nontuberculous mycobacterial lung disease

V Dartois, T Dick - Nature Reviews Drug Discovery, 2024 - nature.com
Tuberculosis (TB) drug discovery and development has undergone nothing short of a
revolution over the past 20 years. Successful public–private partnerships and sustained …

[HTML][HTML] Update of drug-resistant tuberculosis treatment guidelines: A turning point

E Vanino, B Granozzi, OW Akkerman… - International Journal of …, 2023 - Elsevier
Abstract In December 2022 World Health Organization released a new treatment for
multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB) guideline. The main …

Scientific advances and the end of tuberculosis: a report from the Lancet Commission on Tuberculosis

M Reid, YJP Agbassi, N Arinaminpathy, A Bercasio… - The Lancet, 2023 - thelancet.com
Executive summary The 2019 Lancet Commission on Tuberculosis laid out an optimistic
vision for how to build a tuberculosis-free world through smart investments based on sound …

Short oral regimens for pulmonary rifampicin-resistant tuberculosis (TB-PRACTECAL): an open-label, randomised, controlled, phase 2B-3, multi-arm, multicentre, non …

BT Nyang'wa, C Berry, E Kazounis, I Motta… - The Lancet …, 2024 - thelancet.com
Background Around 500 000 people worldwide develop rifampicin-resistant tuberculosis
each year. The proportion of successful treatment outcomes remains low and new …

Recent advances in the treatment of tuberculosis

I Motta, M Boeree, D Chesov, K Dheda… - Clinical Microbiology …, 2024 - Elsevier
Background Tuberculosis (TB) is a global health challenge and one of the leading causes of
death worldwide. In the last decade, the TB treatment landscape has dramatically changed …

The path to tuberculosis elimination: a renewed vision

GB Migliori, D Dowdy, JT Denholm… - European …, 2023 - publications.ersnet.org
Tuberculosis (TB) elimination and pre-elimination, with thresholds of 1 and 10 incident
cases per million population, respectively, were considered achievable for low TB incidence …

Bedaquiline-pretomanid-moxifloxacin-pyrazinamide for drug-sensitive and drug-resistant pulmonary tuberculosis treatment: a phase 2c, open-label, multicentre …

M Cevik, LC Thompson, C Upton, VC Rolla… - The Lancet Infectious …, 2024 - thelancet.com
Background The current tuberculosis (TB) drug development pipeline is being re-populated
with candidates, including nitroimidazoles such as pretomanid, that exhibit a potential to …

TEACHER SOCIO-LINGUISTIC FACTORS AND LEARNING OUTCOMES IN ENGLISH LANGUAGE AMONG PUBLIC SENIOR SECONDARY STUDENTS IN THE …

CO ADIGUN - 2023 - 140.105.46.132
English Language (EL) is a core subject in schools, and success in it is a part of the
requirements for certification and educational advancement. However, evidence has shown …

The safety and tolerability of linezolid in novel short-course regimens containing bedaquiline, pretomanid, and linezolid to treat rifampicin-resistant tuberculosis: an …

T Hasan, E Medcalf, BT Nyang'wa… - Clinical infectious …, 2024 - academic.oup.com
Background Effectiveness, safety, tolerability, and adherence are critical considerations in
shifting to shorter tuberculosis (TB) regimens. Novel 6-month oral regimens that include …