Diabetic macular edema: evidence-based management

DJ Browning, MW Stewart, C Lee - Indian journal of …, 2018 - journals.lww.com
Diabetic macular edema (DME) is the most common cause of vision loss in patients with
diabetic retinopathy with an increasing prevalence tied to the global epidemic in type 2 …

Retinal microglia: just bystander or target for therapy?

M Karlstetter, R Scholz, M Rutar, WT Wong… - Progress in retinal and …, 2015 - Elsevier
Resident microglial cells can be regarded as the immunological watchdogs of the brain and
the retina. They are active sensors of their neuronal microenvironment and rapidly respond …

Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions

I Klaassen, CJF Van Noorden… - Progress in retinal and …, 2013 - Elsevier
Breakdown of the inner endothelial blood-retinal barrier (BRB), as occurs in diabetic
retinopathy, age-related macular degeneration, retinal vein occlusions, uveitis and other …

PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect

S Acharya, SK Sahoo - Advanced drug delivery reviews, 2011 - Elsevier
As mortality due to cancer continues to rise, advances in nanotechnology have significantly
become an effective approach for achieving efficient drug targeting to tumour tissues by …

Pathophysiology of diabetic retinopathy

MW Stewart - Diabetic retinopathy: evidence-based management, 2010 - Springer
The retina was first described by Herophilus of Chalcedon around 300 bc. It was named by
Rufos of Ephesus (c. 110 ad) and appeared to early anatomists as a surrounding net which …

The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina

JP SanGiovanni, EY Chew - Progress in retinal and eye research, 2005 - Elsevier
In this work we advance the hypothesis that omega-3 (ω-3) long-chain polyunsaturated fatty
acids (LCPUFAs) exhibit cytoprotective and cytotherapeutic actions contributing to a number …

One-year outcomes of the da Vinci Study of VEGF Trap-Eye in eyes with diabetic macular edema

DV Do, QD Nguyen, D Boyer, U Schmidt-Erfurth… - Ophthalmology, 2012 - Elsevier
PURPOSE: To compare different doses and dosing regimens of Vascular Endothelial
Growth Factor (VEGF) Trap-Eye with laser photocoagulation in eyes with diabetic macular …

Müller glial cells in retinal disease

A Bringmann, P Wiedemann - Ophthalmologica, 2011 - karger.com
Virtually all pathogenic stimuli activate Müller cells. Reactive Müller cells exert protective
and toxic effects on photoreceptors and neurons. They contribute to oxidative stress and …

Diabetic retinopathy: seeing beyond glucose-induced microvascular disease

DA Antonetti, AJ Barber, SK Bronson, WM Freeman… - Diabetes, 2006 - Am Diabetes Assoc
Diabetic retinopathy remains a frightening prospect to patients and frustrates physicians.
Destruction of damaged retina by photocoagulation remains the primary treatment nearly 50 …

Retinal angiogenesis in development and disease

RF Gariano, TW Gardner - Nature, 2005 - nature.com
The retina has long been regarded as 'an approachable part of the brain'for investigating
neurosensory processes. Cell biologists are now capitalizing on the accessibility of the …