Genetics of global gene expression
A new field of genetic analysis of global gene expression has emerged in recent years,
driven by the realization that traditional techniques of linkage and association analysis can …
driven by the realization that traditional techniques of linkage and association analysis can …
Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution
Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …
continues to afflict hundreds of millions of people every year. Infections with malaria …
PlasmoDB: a functional genomic database for malaria parasites
C Aurrecoechea, J Brestelli, BP Brunk… - Nucleic acids …, 2009 - academic.oup.com
Abstract PlasmoDB (http://PlasmoDB. org) is a functional genomic database for Plasmodium
spp. that provides a resource for data analysis and visualization in a gene-by-gene or …
spp. that provides a resource for data analysis and visualization in a gene-by-gene or …
Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites
Single-cell RNA-sequencing is revolutionising our understanding of seemingly
homogeneous cell populations but has not yet been widely applied to single-celled …
homogeneous cell populations but has not yet been widely applied to single-celled …
New insights into the blood‐stage transcriptome of Plasmodium falciparum using RNA‐Seq
Recent advances in high‐throughput sequencing present a new opportunity to deeply probe
an organism's transcriptome. In this study, we used Illumina‐based massively parallel …
an organism's transcriptome. In this study, we used Illumina‐based massively parallel …
Malaria− an overview
R Tuteja - The FEBS journal, 2007 - Wiley Online Library
Malaria is caused by protozoan parasites of the genus Plasmodium and is a major cause of
mortality and morbidity worldwide. These parasites have a complex life cycle in their …
mortality and morbidity worldwide. These parasites have a complex life cycle in their …
21st century natural product research and drug development and traditional medicines
Covering: 1987 to 2013 Natural products and related structures are essential sources of new
pharmaceuticals, because of the immense variety of functionally relevant secondary …
pharmaceuticals, because of the immense variety of functionally relevant secondary …
A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells
Cerebral malaria is the most deadly manifestation of infection with Plasmodium falciparum.
The pathology of cerebral malaria is characterized by the accumulation of infected …
The pathology of cerebral malaria is characterized by the accumulation of infected …
Transcriptional variation in the malaria parasite Plasmodium falciparum
N Rovira-Graells, AP Gupta, E Planet… - Genome …, 2012 - genome.cshlp.org
Malaria genetic variation has been extensively characterized, but the level of epigenetic
plasticity remains largely unexplored. Here we provide a comprehensive characterization of …
plasticity remains largely unexplored. Here we provide a comprehensive characterization of …
Molecular evidence for the localization of Plasmodium falciparum immature gametocytes in bone marrow
Plasmodium falciparum immature gametocytes are not observed in peripheral blood.
However, gametocyte stages in organs such as bone marrow have never been assessed by …
However, gametocyte stages in organs such as bone marrow have never been assessed by …