Small-angle scattering (SAS) is a technique that is able to probe the structural organization
of matter and quantify its response to changes in external conditions. X-ray and neutron …

Since the first high-resolution structure of the nucleosome was reported in 1997, the
available information on chromatin structure has increased very rapidly. Here, we review …

BioXTAS RAW is a graphical-user-interface-based free open-source Python program for
reduction and analysis of small-angle X-ray solution scattering (SAXS) data. The software is …

Dynamic ensembles of macromolecules mediate essential processes in biology.
Understanding the mechanisms driving the function and molecular interactions …

Intrinsically disordered proteins (IDPs) and IDP regions fail to form a stable structure, yet
they exhibit biological activities. Their mobile flexibility and structural instability are encoded …

Proteins and synthetic polymers can undergo phase transitions in response to changes to
intensive solution parameters such as temperature, proton chemical potentials (pH), and …

Unfolded states of proteins and native states of intrinsically disordered proteins (IDPs)
populate heterogeneous conformational ensembles in solution. The average sizes of these …

Many cell signaling events are coordinated by intrinsically disordered protein regions (IDRs)
that undergo multisite Serine/Threonine phosphorylation. The conformational properties of …

Intrinsically disordered proteins (IDPs) lack well-defined three-dimensional structures, thus
challenging the archetypal notion of structure–function relationships. Determining the …

Intrinsically disordered regions (IDRs) are essential for membrane receptor regulation but
often remain unresolved in structural studies. TRPV4, a member of the TRP vanilloid …