Epilepsy in adults

RD Thijs, R Surges, TJ O'Brien, JW Sander - The lancet, 2019 - thelancet.com
Epilepsy is one of the most common serious brain conditions, affecting over 70 million
people worldwide. Its incidence has a bimodal distribution with the highest risk in infants and …

Adult epilepsy

AA Asadi-Pooya, F Brigo, S Lattanzi, I Blumcke - The Lancet, 2023 - thelancet.com
Epilepsy is a common medical condition that affects people of all ages, races, social classes,
and geographical regions. Diagnosis of epilepsy remains clinical, and ancillary …

Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study

HJ Lamberink, WM Otte, I Blümcke, KPJ Braun… - The Lancet …, 2020 - thelancet.com
Background Surgery is a widely accepted treatment option for drug-resistant focal epilepsy.
A detailed analysis of longitudinal postoperative seizure outcomes and use of antiepileptic …

Predicting neurosurgical outcomes in focal epilepsy patients using computational modelling

N Sinha, J Dauwels, M Kaiser, SS Cash… - Brain, 2017 - academic.oup.com
Abstract See Eissa and Schevon (doi: 10.1093/aww332) for a scientific commentary on this
article. Surgery can be a last resort for patients with intractable, medically refractory epilepsy …

The current place of epilepsy surgery

J Engel Jr - Current opinion in neurology, 2018 - journals.lww.com
Surgical treatment for epilepsy remains underutilized, in part because of persistent
misconceptions. Rather than promote referral for surgery, it would be more appropriate to …

Analysis of morbidity and outcomes associated with use of subdural grids vs stereoelectroencephalography in patients with intractable epilepsy

N Tandon, BA Tong, ER Friedman, JA Johnson… - JAMA …, 2019 - jamanetwork.com
Importance A major change has occurred in the evaluation of epilepsy with the availability of
robotic stereoelectroencephalography (SEEG) for seizure localization. However, the …

Comparative effectiveness of stereotactic electroencephalography versus subdural grids in epilepsy surgery

L Jehi, M Morita‐Sherman, TE Love… - Annals of …, 2021 - Wiley Online Library
Objective The aim was to compare the outcomes of subdural electrode (SDE) implantations
versus stereotactic electroencephalography (SEEG), the 2 predominant methods of …

Predicting seizure recurrence after an initial seizure-like episode from routine clinical notes using large language models: a retrospective cohort study

BK Beaulieu-Jones, MF Villamar, P Scordis… - The Lancet Digital …, 2023 - thelancet.com
Background The evaluation and management of first-time seizure-like events in children can
be difficult because these episodes are not always directly observed and might be epileptic …

Structural brain network abnormalities and the probability of seizure recurrence after epilepsy surgery

N Sinha, Y Wang, N Moreira da Silva, A Miserocchi… - Neurology, 2021 - AAN Enterprises
Objective We assessed preoperative structural brain networks and clinical characteristics of
patients with drug-resistant temporal lobe epilepsy (TLE) to identify correlates of postsurgical …

Surgical treatment for epilepsy: the potential gap between evidence and practice

N Jetté, JW Sander, MR Keezer - The Lancet Neurology, 2016 - thelancet.com
Findings from randomised controlled trials, along with more than 100 case series and
observational studies, support the efficacy and safety of resective surgery and, more …