The role of lncRNA NEAT1 in human cancer chemoresistance

F Long, X Li, J Pan, H Ye, C Di, Y Huang, J Li… - Cancer Cell …, 2024 - Springer
Chemotherapy is currently one of the most effective methods in clinical cancer treatment.
However, chemotherapy resistance is an important reason for poor chemotherapy efficacy …

Advances in smart nanotechnology-supported photodynamic therapy for cancer

G Li, C Wang, B **, T Sun, K Sun, S Wang… - Cell Death Discovery, 2024 - nature.com
Cancer has emerged as a formidable challenge in the 21st century, impacting society, public
health, and the economy. Conventional cancer treatments often exhibit limited efficacy and …

Immune Cell-Derived Exosomes: A Cell-Free Cutting-Edge Tumor Immunotherapy

R Sengupta, IS Topiwala, M Shakthi A… - ACS Applied Bio …, 2024 - ACS Publications
Extracellular vesicles (EVs) are cellular communication molecules and are classified into
three major subpopulations, such as microvesicles, apoptotic bodies, and exosomes …

Encapsulation of a small-molecule drug based on substituted 2-aminothiophenes in calcium carbonate carriers for therapy of melanoma

TE Karpov, A Rogova, DR Akhmetova… - Biomaterials …, 2024 - pubs.rsc.org
Although small molecule drugs are widely used in chemotherapy, their low bioavailability,
low-concentrated dose in the tumor zone, systemic toxicity, and chemoresistance can …

Unlocking the potential of pyroptosis in tumor immunotherapy: a new horizon in cancer treatment

Q Yin, SY Song, Y Bian, Y Wang, A Deng, J Lv… - Frontiers in …, 2024 - frontiersin.org
Background The interaction between pyroptosis—a form of programmed cell death—and
tumor immunity represents a burgeoning field of interest. Pyroptosis exhibits a dual role in …

Harnessing the power of clustered regularly interspaced short palindromic repeats (CRISPR) based microfluidics for next-generation molecular diagnostics

R Kaur, S Gupta, A Chauhan, V Mishra… - Molecular Biology …, 2024 - Springer
CRISPR-based (Clustered regularly interspaced short palindromic repeats-based)
technologies have revolutionized molecular biology and diagnostics, offering …

Design and optimization strategies of PROTACs and its Application, Comparisons to other targeted protein degradation for multiple oncology therapies

M Malarvannan, S Unnikrishnan, S Monohar… - Bioorganic …, 2024 - Elsevier
Recent years have witnessed notable breakthroughs in the field of biotherapeutic, with a
particular emphasis on concentrated research. Proteolysis Targeting Chimeras (PROTACs) …