CONCLUSION The notion that inflammation is the net resultant of pro and contra
inflammatory pathways (Fauve, 1980) is well illustrated by the dual role of neutrophils which …

During the past year, additional insights into systems that regulate antimicrobial peptide
production in Drosophila were reported. Granulysin, a peptide stored in the cytoplasmic …

Macrophages (MPs) are important for skeletal muscle regeneration in vivo and may exert
beneficial effects on myogenic cell growth through mitogenic and antiapoptotic activities in …

Increased leukocyte elastase activity in mice lacking secretory leukocyte protease inhibitor
(SLPI) leads to impaired wound healing due to enhanced activity of TGFβ and perhaps …

A pilot program was undertaken in immune gene discovery in two sister species of
litopenaeid shrimp, the Pacific white shrimp, Litopenaeus vannamei and the Atlantic white …

The immune system is continuously challenged with large quantities of exogenous antigens
at the barriers between the external environment and internal human tissues. Antimicrobial …

Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in
normal homoeostasis and at sites of inflammation. These include antiprotease and …

The complement activation product, C5a, is a powerful phlogistic factor. Using antibodies to
detect human or rat C5a, incubation at pH 7.4 of human blood neutrophils or rat alveolar …

The development and resolution of an inflammatory process are regulated by a complex
interplay among cytokines that have pro-and anti-inflammatory effects. Effective and …

The liver is an immunoregulatory organ in which a tolerogenic microenvironment mitigates
the relative “strength” of local immune responses. Paradoxically, necro-inflammatory …