Endometrial immune dysfunction in recurrent pregnancy loss

C Ticconi, A Pietropolli, N Di Simone… - International journal of …, 2019 - mdpi.com
Recurrent pregnancy loss (RPL) represents an unresolved problem for contemporary
gynecology and obstetrics. In fact, it is not only a relevant complication of pregnancy, but is …

Seminal plasma: relevant for fertility?

H Rodriguez-Martinez, EA Martinez, JJ Calvete… - International Journal of …, 2021 - mdpi.com
Seminal plasma (SP), the non-cellular component of semen, is a heterogeneous composite
fluid built by secretions of the testis, the epididymis and the accessory sexual glands. Its …

[HTML][HTML] The female response to seminal fluid

JE Schjenken, SA Robertson - Physiological reviews, 2020 - journals.physiology.org
Seminal fluid is often assumed to have just one function in mammalian reproduction,
delivering sperm to fertilize oocytes. But seminal fluid also transmits signaling agents that …

The microRNA signature of mouse spermatozoa is substantially modified during epididymal maturation

B Nixon, SJ Stanger, BP Mihalas, JN Reilly… - Biology of …, 2015 - academic.oup.com
In recent years considerable effort has been devoted to understanding the epigenetic control
of sperm development, leading to an increased appreciation of the importance of RNA …

Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?

RJ Aitken, MA Baker, B Nixon - Asian Journal of Andrology, 2015 - journals.lww.com
This chapter explores the possibility that capacitation and apoptosis are linked processes
joined by their common dependence on the continued generation of reactive oxygen …

Uterine luminal epithelium as the transient gateway for embryo implantation

X Ye - Trends in Endocrinology & Metabolism, 2020 - cell.com
The uterine luminal epithelium (LE) is the first maternal contact for an implanting embryo.
Intrauterine fluid resorption, cessation of LE proliferation and apoptosis, and LE structural …

Embryotoxic cytokines—Potential roles in embryo loss and fetal programming

SA Robertson, PY Chin, JG Femia… - Journal of reproductive …, 2018 - Elsevier
Cytokines in the reproductive tract environment at conception mediate a dialogue between
the embryo and maternal tissues to profoundly influence embryo development and …

[HTML][HTML] Seminal fluid and fertility in women

SA Robertson, DJ Sharkey - Fertility and sterility, 2016 - Elsevier
Seminal fluid is often viewed as simply a vehicle to carry sperm to fertilize the oocyte, but a
more complex function in influencing female reproductive physiology is now evident …

Seminal plasma proteomes and sperm fertility

X Druart, S de Graaf - Animal reproduction science, 2018 - Elsevier
During ejaculation, the spermatozoa are transported by the seminal plasma, a fluid resulting
from secretions originating mainly from the prostate and the seminal vesicles in mammals …

The influence of seminal plasma on offspring development and health

HL Morgan, AJ Watkins - Seminars in cell & developmental biology, 2020 - Elsevier
The concept that a father's wellbeing at the time of conception influences the development
and long-term health of his offspring is now well established. However, the mechanisms …