Genomics in personalized nutrition: can you “eat for your genes”?

VA Mullins, W Bresette, L Johnstone, B Hallmark… - Nutrients, 2020 - mdpi.com
Genome-wide single nucleotide polymorphism (SNP) data are now quickly and
inexpensively acquired, raising the prospect of creating personalized dietary …

New insights regarding genetic aspects of childhood obesity: a minireview

CO Mǎrginean, C Mǎrginean, LE Meliţ - Frontiers in pediatrics, 2018 - frontiersin.org
Introduction: Childhood obesity is occurring at alarming rates in both developed and
develo** countries.“Obesogenic” environmental factors must be associated with variants …

[HTML][HTML] Screening of obese offspring of first-cousin consanguineous subjects for the angiotensin-converting enzyme gene with a 287-bp Alu sequence

AF Alshammary, IA Khan - Journal of obesity & metabolic syndrome, 2021 - ncbi.nlm.nih.gov
Background Consanguinity, defined as a blood relation between couples, is associated with
genetic diseases in their offspring. In Saudi Arabia, obesity is considered a major health …

Nutrigenetics—personalized nutrition in obesity and cardiovascular diseases

L Barrea, G Annunziata, L Bordoni… - International journal of …, 2020 - nature.com
Epidemiological data support the view that both obesity and cardiovascular diseases (CVD)
account for a high proportion of total morbidity and mortality in adults throughout the world …

Insights into the multifactorial causation of obesity by integrated genetic and epigenetic analysis

S Diels, W Vanden Berghe, W Van Hul - Obesity Reviews, 2020 - Wiley Online Library
Obesity is a highly heritable multifactorial disease that places an enormous burden on
human health. Its increasing prevalence and the concomitant‐reduced life expectancy has …

Genetic polymorphisms associated with obesity in the Arab world: a systematic review

S Younes, A Ibrahim, R Al-Jurf, H Zayed - International Journal of …, 2021 - nature.com
Background Obesity, one of the most common chronic health conditions worldwide, is a
multifactorial disease caused by complex genetic and environmental interactions. Several …

Development of a genetic risk score for obesity predisposition evaluation

N Damavandi, A Soleymaniniya… - Molecular Genetics and …, 2022 - Springer
Obesity is a major public health issue resulting from an interaction between genetic and
environmental factors. Genetic risk scores (GRSs) are useful to summarize the effects of …

[HTML][HTML] Polymorphisms on rs9939609 FTO and rs17782313 MC4R genes in children and adolescent obesity: A systematic review

CMM Resende, HAM da Silva, CP Campello… - Nutrition, 2021 - Elsevier
The aim of this review was to assess whether the presence of rs9939609 and rs17782313
polymorphisms increase the risk for obesity among children and adolescents. This …

Mitochondrial DNA methylation and copy number predict body composition in a young female population

L Bordoni, V Smerilli, C Nasuti… - Journal of Translational …, 2019 - Springer
Background Since both genomic and environmental factors are involved in obesity etiology,
several studies about the influence of adiposity on both nuclear DNA and mitochondrial …

Methylation and Expression of FTO and PLAG1 Genes in Childhood Obesity: Insight into Anthropometric Parameters and Glucose–Lipid Metabolism

W Czogała, M Czogała, W Strojny, G Wątor, P Wołkow… - Nutrients, 2021 - mdpi.com
The occurrence of childhood obesity is influenced by both genetic and epigenetic factors.
FTO (FTO alpha-ketoglutarate dependent dioxygenase) is a gene of well-established …