Ferritin nanocage: A promising and designable multi-module platform for constructing dynamic nanoassembly-based drug nanocarrier
Ferritin has been widely recognized as an ideal drug delivery vehicle owing to its unique
cage-like structure. Coupled with intrinsic targeting ability and excellent biosafety, ferritin …
cage-like structure. Coupled with intrinsic targeting ability and excellent biosafety, ferritin …
Bioengineering strategies for protein-based nanoparticles
In recent years, the practical application of protein-based nanoparticles (PNPs) has
expanded rapidly into areas like drug delivery, vaccine development, and biocatalysis …
expanded rapidly into areas like drug delivery, vaccine development, and biocatalysis …
Antigen-and scaffold-specific antibody responses to protein nanoparticle immunogens
Protein nanoparticle scaffolds are increasingly used in next-generation vaccine designs,
and several have established records of clinical safety and efficacy. Yet the rules for how …
and several have established records of clinical safety and efficacy. Yet the rules for how …
Comparison of exosomes and ferritin protein nanocages for the delivery of membrane protein therapeutics
Exosomes are small membrane vesicles secreted by most cell types that play an important
role in intercellular communication. Due to the characteristic of transferring their …
role in intercellular communication. Due to the characteristic of transferring their …
[HTML][HTML] The right Timing, right combination, right sequence, and right delivery for Cancer immunotherapy
Cancer immunotherapy (CI) represented by immune checkpoint inhibitors (ICIs) presents a
new paradigm for cancer treatment. However, the types of cancer that attain a therapeutic …
new paradigm for cancer treatment. However, the types of cancer that attain a therapeutic …
Develo** protein-based nanoparticles as versatile delivery systems for cancer therapy and imaging
In recent years, it has become apparent that cancer nanomedicine's reliance on synthetic
nanoparticles as drug delivery systems has resulted in limited clinical outcomes. This is …
nanoparticles as drug delivery systems has resulted in limited clinical outcomes. This is …
Taking advantage of cellular uptake of ferritin nanocages for targeted drug delivery
The search for ideal nanocarrier, which could be rapidly translated to clinical practice, is still
ongoing over the past few decades. However, many reviews are focused on important …
ongoing over the past few decades. However, many reviews are focused on important …
[HTML][HTML] Artificial scaffold polypeptides as an efficient tool for the targeted delivery of nanostructures in vitro and in vivo
VO Shipunova, SM Deyev - Acta naturae, 2022 - ncbi.nlm.nih.gov
The use of traditional tools for the targeted delivery of nanostructures, such as antibodies,
transferrin, lectins, or aptamers, often leads to an entire range of undesirable effects. The …
transferrin, lectins, or aptamers, often leads to an entire range of undesirable effects. The …
Protein-based nanocages for vaccine development
Protein nanocages have attracted considerable attention in various fields of nanomedicine
due to their intrinsic properties, including biocompatibility, biodegradability, high structural …
due to their intrinsic properties, including biocompatibility, biodegradability, high structural …
Construction of surface-modified polydopamine nanoparticles for sequential drug release and combined chemo-photothermal cancer therapy
C Wei, P Wang, Z Huang, D He, W Zhu… - Molecular …, 2021 - ACS Publications
Single chemotherapy often causes severe adverse effects and drug resistance to limit
therapeutic efficacy. As a noninvasive approach, photothermal therapy (PTT) represents an …
therapeutic efficacy. As a noninvasive approach, photothermal therapy (PTT) represents an …