The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses

SM Murray, AM Ansari, J Frater, P Klenerman… - Nature Reviews …, 2023 - nature.com
Pre-existing cross-reactive immune responses to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) proteins in infection-naive subjects have been described by …

[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy

BH Kok, HT Lim, CP Lim, NS Lai, CY Leow, CH Leow - Virus research, 2023 - Elsevier
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

Dengue: update on clinically relevant therapeutic strategies and vaccines

M Palanichamy Kala, AL St. John… - Current Treatment Options …, 2023 - Springer
Opinion statement Dengue viruses (DENV) continue to circulate worldwide, resulting in a
significant burden on human health. There are four antigenically distinct serotypes of DENV …

Beyond binding: antibody effector functions in infectious diseases

LL Lu, TJ Suscovich, SM Fortune, G Alter - Nature Reviews Immunology, 2018 - nature.com
Antibodies play an essential role in host defence against pathogens by recognizing
microorganisms or infected cells. Although preventing pathogen entry is one potential …

Adaptive immune responses to primary and secondary dengue virus infections

AL St. John, APS Rathore - Nature Reviews Immunology, 2019 - nature.com
Dengue is the leading mosquito-borne viral illness infecting humans. Owing to the
circulation of multiple serotypes, global expansion of the disease and recent gains in …

Rapid development of a DNA vaccine for Zika virus

KA Dowd, SY Ko, KM Morabito, ES Yang, RS Pelc… - Science, 2016 - science.org
Zika virus (ZIKV) was identified as a cause of congenital disease during the explosive
outbreak in the Americas and Caribbean that began in 2015. Because of the ongoing fetal …

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

G Sapparapu, E Fernandez, N Kose, B Cao, JM Fox… - Nature, 2016 - nature.com
Zika virus (ZIKV) is an emerging mosquito-transmitted flavivirus that can cause severe
disease, including congenital birth defects during pregnancy 1. To develop candidate …

Immune response to dengue and Zika

A Elong Ngono, S Shresta - Annual review of immunology, 2018 - annualreviews.org
Flaviviruses such as dengue (DENV), yellow fever (YFV), West Nile (WNV), and Zika (ZIKV)
are human pathogens of global significance. In particular, DENV causes the most prevalent …

Structural basis of Zika virus-specific antibody protection

H Zhao, E Fernandez, KA Dowd, SD Speer, DJ Platt… - Cell, 2016 - cell.com
Zika virus (ZIKV) infection during pregnancy has emerged as a global public health problem
because of its ability to cause severe congenital disease. Here, we developed six mouse …

New insights into the immunopathology and control of dengue virus infection

G Screaton, J Mongkolsapaya, S Yacoub… - Nature Reviews …, 2015 - nature.com
Dengue virus poses a major threat to global public health: two-thirds of the world's
population is now at risk from infection by this mosquito-borne virus. Dengue virus causes a …