Obesity and cardiovascular disease: a scientific statement from the American Heart Association

TM Powell-Wiley, P Poirier, LE Burke, JP Després… - Circulation, 2021 - Am Heart Assoc
The global obesity epidemic is well established, with increases in obesity prevalence for
most countries since the 1980s. Obesity contributes directly to incident cardiovascular risk …

Obesity phenotypes, diabetes, and cardiovascular diseases

ME Piché, A Tchernof, JP Després - Circulation research, 2020 - Am Heart Assoc
This review addresses the interplay between obesity, type 2 diabetes mellitus, and
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …

2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation

H Calkins, G Hindricks, R Cappato, YH Kim… - Ep …, 2018 - academic.oup.com
AFL atrial flutter AH arterial hypertension ANS autonomic nervous system APD action
potential duration ARREST-AF Aggressive Risk Factor Reduction Study for Atrial Fibrillation …

Obesity and atrial fibrillation prevalence, pathogenesis, and prognosis: effects of weight loss and exercise

CJ Lavie, A Pandey, DH Lau, MA Alpert… - Journal of the American …, 2017 - jacc.org
Both obesity and atrial fibrillation (AF) are increasing in epidemic proportions, and both
increase the prevalence of cardiovascular disease events. Obesity has adverse effects on …

Cardiac fibrosis in patients with atrial fibrillation: mechanisms and clinical implications

MS Dzeshka, GYH Lip, V Snezhitskiy… - Journal of the American …, 2015 - jacc.org
Atrial fibrillation (AF) is associated with structural, electrical, and contractile remodeling of
the atria. Development and progression of atrial fibrosis is the hallmark of structural …

Impact of CARDIOrespiratory FITness on arrhythmia recurrence in obese individuals with atrial fibrillation: the CARDIO-FIT study

RK Pathak, A Elliott, ME Middeldorp, M Meredith… - Journal of the American …, 2015 - jacc.org
Background: Obesity begets atrial fibrillation (AF). Although cardiorespiratory fitness is
protective against incident AF in obese individuals, its effect on AF recurrence or the benefit …

Mechanisms underlying direct actions of hyperlipidemia on myocardium: an updated review

YS Yao, TD Li, ZH Zeng - Lipids in Health and Disease, 2020 - Springer
Hyperlipidemia is a common metabolic disorder and one of risk factors for cardiovascular
disease. Clinical studies have shown that hyperlipidemia increases the risk of non-ischemic …

Associations of epicardial, abdominal, and overall adiposity with atrial fibrillation

CX Wong, MT Sun, A Odutayo, CA Emdin… - Circulation …, 2016 - Am Heart Assoc
Background—Although adiposity is increasingly recognized as a risk factor for atrial
fibrillation (AF), the importance of epicardial fat compared with other adipose tissue depots …

Novel mechanisms in the pathogenesis of atrial fibrillation: practical applications

DH Lau, U Schotten, R Mahajan, NA Antic… - European heart …, 2016 - academic.oup.com
Intensive research over the last few decades has seen significant advances in our
understanding of the complex mechanisms underlying atrial fibrillation (AF). The epidemic of …

Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation

S Nattel, D Dobrev - Nature Reviews Cardiology, 2016 - nature.com
Atrial fibrillation (AF) is an extremely prevalent arrhythmia that presents a wide range of
therapeutic challenges. AF usually begins in a self-terminating paroxysmal form (pAF). With …