BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

The management of acute ischemic stroke has undergone a paradigm shift in the past
decade. This has been spearheaded by the emergence of endovascular thrombectomy …

Importance Prehospital transfer protocols are based on rapid access to reperfusion
therapies for patients with ischemic stroke. The effect of different protocols among patients …

Importance The benefit of intravenous thrombolysis (IVT) for acute ischemic stroke declines
with longer time from symptom onset, but it is not known whether a similar time dependency …

Objective Tenecteplase improves reperfusion compared to alteplase in patients with large
vessel occlusions. To determine whether this improvement varies across the spectrum of …

Background Recent clinical trials investigating endovascular therapy in the extended time
window have opened new treatment paradigms for patients with late‐presenting large …

Mechanical thrombectomy is a ground breaking treatment for acute ischaemic stroke caused
by occlusion of a large vessel. Its efficacy over intravenous thrombolysis has been proven in …

Background and Objectives Endovascular thrombectomy (EVT) is standard treatment for
anterior large vessel occlusion stroke (LVO-a stroke). Prehospital diagnosis of LVO-a stroke …

Background Timely treatment of acute stroke depends on early identification and triage.
Improved methods for recognition of stroke in the prehospital setting are needed. We aimed …

Background: Futile reperfusion (FR) is becoming an urgent issue for acute ischemic stroke
patients who underwent endovascular treatment (EVT). Although the recanalization rate has …