Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis

E Schneider, KJ O'Riordan, G Clarke, JF Cryan - Nature metabolism, 2024 - nature.com
The prevalence of brain disorders, including stress-related neuropsychiatric disorders and
conditions with cognitive dysfunction, is rising. Poor dietary habits contribute substantially to …

[HTML][HTML] The efficacy of Probiotics, Prebiotics, Synbiotics, and fecal microbiota transplantation in irritable bowel syndrome: a systematic review and network Meta …

Y Wu, Y Li, Q Zheng, L Li - Nutrients, 2024 - mdpi.com
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder with gut microbiota
imbalance playing a significant role. There are increasing numbers of research studies …

The gut microbiome in disorders of gut–brain interaction

N Kraimi, T Ross, J Pujo, G De Palma - Gut Microbes, 2024 - Taylor & Francis
Functional gastrointestinal disorders (FGIDs), chronic disorders characterized by either
abdominal pain, altered intestinal motility, or their combination, have a worldwide …

The importance of the gut microbiome and its signals for a healthy nervous system and the multifaceted mechanisms of neuropsychiatric disorders

L Riehl, J Fürst, M Kress, N Rykalo - Frontiers in Neuroscience, 2024 - frontiersin.org
Increasing evidence links the gut microbiome and the nervous system in health and disease.
This narrative review discusses current views on the interaction between the gut microbiota …

From bugs to brain: unravelling the GABA signalling networks in the brain-gut-microbiome axis

D Belelli, JJ Lambert, MLY Wan, AR Monteiro, DJ Nutt… - Brain, 2024 - academic.oup.com
Convergent data, across species, paint a compelling picture of the critical role of the gut and
its resident microbiota in several brain functions and disorders. The chemicals mediating …

Depression and risk of gastrointestinal disorders: a comprehensive two-sample Mendelian randomization study of European ancestry

D Chen, Y Zhang, T Huang, J Jia - Psychological Medicine, 2023 - cambridge.org
BackgroundMajor depressive disorder (MDD) is clinically documented to co-occur with
multiple gastrointestinal disorders (GID), but the potential causal relationship between them …

Efficacy of different dietary patterns in the treatment of functional gastrointestinal disorders in children and adolescents: a systematic review of intervention studies

CN Katsagoni, VM Karagianni, A Papadopoulou - Nutrients, 2023 - mdpi.com
Functional gastrointestinal disorders (FGIDs) are common in children and adolescents. In
recent years, interest in the role of diet in the treatment of FGIDs has increased. Currently …

Irritable bowel syndrome: When food is a pain in the gut

H Hussein, S Van Remoortel… - Immunological …, 2024 - Wiley Online Library
Irritable bowel syndrome (IBS) is a chronic gastrointestinal condition associated with altered
bowel habits and recurrent abdominal pain, often triggered by food intake. Current …

Sexually Dimorphic Effects of Histamine Degradation by Enteric Glial Histamine N-Methyltransferase (HNMT) on Visceral Hypersensitivity

JL McClain, W Morales-Soto, J Gonzales, V Parmar… - Biomolecules, 2023 - mdpi.com
Histamine is a neuromodulator that affects gut motility and visceral sensitivity through
intrinsic and extrinsic neural pathways, yet the mechanisms regulating histamine availability …

Advances in brain-gut-microbiome interactions: a comprehensive update on signaling mechanisms, disorders, and therapeutic implications

TS Dong, E Mayer - Cellular and molecular gastroenterology and …, 2024 - Elsevier
The complex, bidirectional interactions between the brain, the gut and the gut microbes are
best referred to as the Brain Gut Microbiome system. Animal and clinical studies have …