Nanosecond pulsed electric field (nsPEF): Opening the biotechnological Pandora's box
Nanosecond Pulsed Electric Field (nsPEF) is an electrostimulation technique first developed
in 1995; nsPEF requires the delivery of a series of pulses of high electric fields in the order of …
in 1995; nsPEF requires the delivery of a series of pulses of high electric fields in the order of …
Electroporation and cell killing by milli-to nanosecond pulses and avoiding neuromuscular stimulation in cancer ablation
Ablation therapies aim at eradication of tumors with minimal impact on surrounding healthy
tissues. Conventional pulsed electric field (PEF) treatments cause pain and muscle …
tissues. Conventional pulsed electric field (PEF) treatments cause pain and muscle …
Perspective on pulsed electric field treatment in the bio-based industry
The bio-based industry is urged to find solutions to meet the demands of a growing world
population. In this context, increased resource efficiency is a major goal. Pulsed electric field …
population. In this context, increased resource efficiency is a major goal. Pulsed electric field …
Nanosecond pulsed electric fields induce endoplasmic reticulum stress accompanied by immunogenic cell death in murine models of lymphoma and colorectal …
Depending on the initiating stimulus, cancer cell death can be immunogenic or non-
immunogenic. Inducers of immunogenic cell death (ICD) rely on endoplasmic reticulum (ER) …
immunogenic. Inducers of immunogenic cell death (ICD) rely on endoplasmic reticulum (ER) …
Human cardiomyocytes are more susceptible to irreversible electroporation by pulsed electric field than human esophageal cells
Pulse electric field‐based (PEF) ablation is a technique whereby short high‐intensity electric
fields inducing irreversible electroporation (IRE) are applied to various tissues. Here, we …
fields inducing irreversible electroporation (IRE) are applied to various tissues. Here, we …
Susceptibility of various human cancer cell lines to nanosecond and microsecond range electrochemotherapy: Feasibility of multi-drug cocktails
Electrochemotherapy (ECT) involves combining anticancer drugs with electroporation,
which is induced by pulsed electric fields (PEFs), while the effects vary in effectiveness …
which is induced by pulsed electric fields (PEFs), while the effects vary in effectiveness …
Pulse width and intensity effects of pulsed electric fields on cancerous and normal skin cells
X Rao, S Chen, Y Alfadhl, X Chen, L Sun, L Yu… - Scientific Reports, 2022 - nature.com
Microsecond pulsed electric fields (PEF) have previously been used for various tumour
therapies, such as gene therapy, electrochemotherapy and irreversible electroporation …
therapies, such as gene therapy, electrochemotherapy and irreversible electroporation …
Excitation and electroporation by MHz bursts of nanosecond stimuli
Intense nanosecond pulsed electric field (nsPEF) is a novel modality for cell activation and
nanoelectroporation. Applications of nsPEF in research and therapy are hindered by a high …
nanoelectroporation. Applications of nsPEF in research and therapy are hindered by a high …
[HTML][HTML] Expression of voltage-gated calcium channels augments cell susceptibility to membrane disruption by nanosecond pulsed electric field
We compared membrane permeabilization by nanosecond pulsed electric field (nsPEF) in
HEK293 cells with and without assembled CaV1. 3 L-type voltage-gated calcium channel …
HEK293 cells with and without assembled CaV1. 3 L-type voltage-gated calcium channel …
Calcium electroporation causes ATP depletion in cells and is effective both in microsecond and nanosecond pulse range as a modality of electrochemotherapy
Calcium electroporation is a modality of electrochemotherapy (ECT), which is based on
intracellular electric field-mediated delivery of cytotoxic doses of calcium into the cells …
intracellular electric field-mediated delivery of cytotoxic doses of calcium into the cells …