Peroxisome proliferator-activated receptors (PPARs) are fatty acid-activated transcription
factors of nuclear hormone receptor superfamily that regulate energy metabolism. Currently …

In recent years, researchers have become focused on the relationship between lipids and
bone metabolism balance. Moreover, many diseases related to lipid metabolism disorders …

Over 25 years have passed since peroxisome proliferators‐activated receptors (PPARs),
were first described. Like other members of the nuclear receptors superfamily, PPARs have …

Non-alcoholic fatty liver disease (NAFLD) is a global health burden closely linked to insulin
resistance, obesity, and type 2 diabetes. The complex pathophysiology of NAFLD involves …

Virtual small molecule libraries are valuable resources for identifying bioactive compounds
in virtual screening campaigns and improving the quality of libraries in terms of …

Introduction: Peroxisome proliferator-activated receptors (PPARs) are the molecular targets
of hypolipidemic and insulin-sensitizing drugs and implicated in a multitude of processes …

The chlorogenic acid (CGA) is a natural product isolated from Cecropia obtusifolia, which
possesses several pharmacological properties, such as: anti-carcinogenic, neuroprotective …

Atherosclerosis is the hallmark of cardiovascular disease (CVD) which is a leading cause of
death in type 2 diabetes patients, and glycemic control is not beneficial in reducing the …

The prevalence of metabolic diseases, including type 2 diabetes, obesity, and
cardiovascular disease, has rapidly increased, yet the molecular mechanisms underlying …

Background The peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-
dependent transcription factor involved in many aspects of metabolism, immune response …