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Smart breeding driven by big data, artificial intelligence, and integrated genomic-enviromic prediction
The first paradigm of plant breeding involves direct selection-based phenotypic observation,
followed by predictive breeding using statistical models for quantitative traits constructed …
followed by predictive breeding using statistical models for quantitative traits constructed …
Artificial intelligence assists precision medicine in cancer treatment
Cancer is a major medical problem worldwide. Due to its high heterogeneity, the use of the
same drugs or surgical methods in patients with the same tumor may have different curative …
same drugs or surgical methods in patients with the same tumor may have different curative …
A roadmap for multi-omics data integration using deep learning
High-throughput next-generation sequencing now makes it possible to generate a vast
amount of multi-omics data for various applications. These data have revolutionized …
amount of multi-omics data for various applications. These data have revolutionized …
[HTML][HTML] Integration strategies of multi-omics data for machine learning analysis
Increased availability of high-throughput technologies has generated an ever-growing
number of omics data that seek to portray many different but complementary biological …
number of omics data that seek to portray many different but complementary biological …
Principles and challenges of modeling temporal and spatial omics data
Studies with temporal or spatial resolution are crucial to understand the molecular dynamics
and spatial dependencies underlying a biological process or system. With advances in high …
and spatial dependencies underlying a biological process or system. With advances in high …
Missing data in multi-omics integration: Recent advances through artificial intelligence
JE Flores, DM Claborne, ZD Weller… - Frontiers in artificial …, 2023 - frontiersin.org
Biological systems function through complex interactions between various 'omics
(biomolecules), and a more complete understanding of these systems is only possible …
(biomolecules), and a more complete understanding of these systems is only possible …
Multimodal deep learning approaches for single-cell multi-omics data integration
Integrating single-cell multi-omics data is a challenging task that has led to new insights into
complex cellular systems. Various computational methods have been proposed to effectively …
complex cellular systems. Various computational methods have been proposed to effectively …
Unsupervised multi-omics data integration methods: a comprehensive review
Through the developments of Omics technologies and dissemination of large-scale
datasets, such as those from The Cancer Genome Atlas, Alzheimer's Disease Neuroimaging …
datasets, such as those from The Cancer Genome Atlas, Alzheimer's Disease Neuroimaging …
Dealing with missing values in proteomics data
Proteomics data are often plagued with missingness issues. These missing values (MVs)
threaten the integrity of subsequent statistical analyses by reduction of statistical power …
threaten the integrity of subsequent statistical analyses by reduction of statistical power …
Multi-omics analysis: Paving the path toward achieving precision medicine in cancer treatment and immuno-oncology
V Raufaste-Cazavieille, R Santiago… - Frontiers in Molecular …, 2022 - frontiersin.org
The acceleration of large-scale sequencing and the progress in high-throughput
computational analyses, defined as omics, was a hallmark for the comprehension of the …
computational analyses, defined as omics, was a hallmark for the comprehension of the …