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Coumarin-based derivatives with potential anti-HIV activity
Z Xu, Q Chen, Y Zhang, C Liang - Fitoterapia, 2021 - Elsevier
Acquired immunodeficiency syndrome (AIDS), as a result of human immunodeficiency virus
(HIV) infection which leads to severe suppression of immune functions, is an enormous …
(HIV) infection which leads to severe suppression of immune functions, is an enormous …
[HTML][HTML] Recent Progress in Synthesis, POM Analyses and SAR of Coumarin-Hybrids as Potential Anti-HIV Agents—A Mini Review
The human immunodeficiency virus (HIV) is the primary cause of acquired immune
deficiency syndrome (AIDS), one of the deadliest pandemic diseases. Various mechanisms …
deficiency syndrome (AIDS), one of the deadliest pandemic diseases. Various mechanisms …
1, 3-Dipolar cycloadditions: applications to the synthesis of antiviral agents
C Nájera, JM Sansano - Organic & biomolecular chemistry, 2009 - pubs.rsc.org
In the present perspective the advances and real possibilities of 1, 3-dipolar cycloadditions
as key steps in the total synthesis of virus inhibitors are described. Azides, nitrones, and …
as key steps in the total synthesis of virus inhibitors are described. Azides, nitrones, and …
[HTML][HTML] Novel coumarin derivatives containing 1, 2, 4-triazole, 4, 5-dicyanoimidazole and purine moieties: Synthesis and evaluation of their cytostatic activity
We report here on the synthesis and in vitro anti-tumor effects of a series of novel 1, 2, 4-
triazole (compounds 3–6), 4, 5-dicyanoimidazole (compound 7), and purine (compounds 8 …
triazole (compounds 3–6), 4, 5-dicyanoimidazole (compound 7), and purine (compounds 8 …
[HTML][HTML] In vivo anticancer and histopathology studies of Schiff bases on Ehrlich ascitic carcinoma cells: 1st cancer update
Three Schiff bases in two different concentrations were evaluated for their anti-tumor activity
against Ehrlich ascites carcinoma (EAC) bearing Swiss albino mice. The in vivo anti-tumor …
against Ehrlich ascites carcinoma (EAC) bearing Swiss albino mice. The in vivo anti-tumor …
[PDF][PDF] Synthesis, antitumor activity and molecular docking study of novel benzofuran-2-yl pyrazole pyrimidine derivatives
MI El-Zahar, SSA El-Karim, ME Haiba… - Acta Pol Pharm Drug Res, 2011 - ptfarm.pl
A new series of (benzofuran-2-yl)-1-phenyl-1H-pyrazol-4-yl) pyrimidine derivatives were
synthesized from 3-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-4-carbaldehyde (1) through …
synthesized from 3-(benzofuran-2-yl)-1-phenyl-1H-pyrazol-4-carbaldehyde (1) through …
[PDF][PDF] Synthesis, characterization and anticancer activity of 1, 2, 4-Triazolo [3, 4-b]-1, 3, 4-thiadiazoles on Hep G2 cell lines
Abstract A series of 3, 6-disubstituted 1, 2, 4–triazolo [3, 4-b]-1, 3, 4-thiadiazoles were
synthesized from 3-substituted-4-amino-5-mercapto-1, 2, 4-triazoles and 3-substituted 4 …
synthesized from 3-substituted-4-amino-5-mercapto-1, 2, 4-triazoles and 3-substituted 4 …
Synthesis of arylated coumarins by Suzuki–Miyaura cross-coupling. Reactions and anti-HIV activity
AM Hamdy, Z Khaddour, NA Al-Masoudi… - Bioorganic & Medicinal …, 2016 - Elsevier
Arylated coumarins were prepared by site-selective Suzuki–Miyaura cross-coupling reaction
of the bis (triflate) of 4-methyl-6, 7-dihydroxycoumarin. Triarylated coumarins were prepared …
of the bis (triflate) of 4-methyl-6, 7-dihydroxycoumarin. Triarylated coumarins were prepared …
10-(4-Hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-3-methyl-1H, 10H-pyrano [4, 3-b] chromen-1-ones from a pseudo-multicomponent reaction and evaluation of their …
Abstract A series of novel 10-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-3-methyl-1H, 10H-
pyrano [4, 3-b] chromen-1-ones were synthesized by a pseudo-three-component reaction of …
pyrano [4, 3-b] chromen-1-ones were synthesized by a pseudo-three-component reaction of …
Convenient synthesis of novel geiparvarin analogs with potential anti-cancer activity via click chemistry
Y Zhang, Z Lv, H Zhong, D Geng, M Zhang… - European journal of …, 2012 - Elsevier
Based on the advantages of natural products in new anti-cancer drug development, we
synthesized a series of novel benzopyran-4-one derivatives and evaluated their in vitro anti …
synthesized a series of novel benzopyran-4-one derivatives and evaluated their in vitro anti …