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[HTML][HTML] Challenges and opportunities of implementing data fusion in process analytical technology—a review
The release of the FDA's guidance on Process Analytical Technology has motivated and
supported the pharmaceutical industry to deliver consistent quality medicine by acquiring a …
supported the pharmaceutical industry to deliver consistent quality medicine by acquiring a …
Pharmaceutical application of multivariate modelling techniques: a review on the manufacturing of tablets
G Shi, L Lin, Y Liu, G Chen, Y Luo, Y Wu, H Li - RSC advances, 2021 - pubs.rsc.org
The tablet manufacturing process is a complex system, especially in continuous
manufacturing (CM). It includes multiple unit operations, such as mixing, granulation, and …
manufacturing (CM). It includes multiple unit operations, such as mixing, granulation, and …
[HTML][HTML] A novel fault detection and diagnosis approach based on orthogonal autoencoders
In recent years, there have been studies focusing on the use of different types of
autoencoders (AEs) for monitoring complex nonlinear data coming from industrial and …
autoencoders (AEs) for monitoring complex nonlinear data coming from industrial and …
Process optimization of twin-screw melt granulation of fenofibrate using design of experiment (DoE)
The purpose of this study was to optimize the melt granulation process of fenofibrate using
twin-screw granulator. Initial screening was performed to select the excipients required for …
twin-screw granulator. Initial screening was performed to select the excipients required for …
Detecting mean changes in experience sampling data in real time: A comparison of univariate and multivariate statistical process control methods.
Detecting early warning signals of develo** mood disorders in continuously collected
affective experience sampling (ESM) data would pave the way for timely intervention and …
affective experience sampling (ESM) data would pave the way for timely intervention and …
How can oral paediatric formulations be improved? A challenge for the XXI century
M Moreira, M Sarraguça - International journal of pharmaceutics, 2020 - Elsevier
Paediatric oral formulations need to be improved. This is an indisputable fact that has gain
attention from the regulators, the medical staff, and researchers. The lack of adequate …
attention from the regulators, the medical staff, and researchers. The lack of adequate …
A deep learning framework for quality control process in the motor oil industry
Given the advancements in the modern world, using Multivariate-Multistage Quality Control
(MVMSQC) patterns in continuous production industries is deemed crucial and essential …
(MVMSQC) patterns in continuous production industries is deemed crucial and essential …
Integrated continuous manufacturing in pharmaceutical industry: current evolutionary steps toward revolutionary future
NA Helal, O Elnoweam, HA Eassa… - Pharmaceutical …, 2019 - Taylor & Francis
Continuous manufacturing (CM) has the potential to provide pharmaceutical products with
better quality, improved yield and with reduced cost and time. Moreover, ease of scale-up …
better quality, improved yield and with reduced cost and time. Moreover, ease of scale-up …
[HTML][HTML] Machine learning on white mica short-wave infrared (SWIR) spectral data in the Tengjia Au deposit, Jiaodong peninsula (Eastern China): A prospecting …
Lode gold deposits are the primary source of global gold resources and possess significant
mineralization potential at depth, necessitating new strategies to locate deep concealed …
mineralization potential at depth, necessitating new strategies to locate deep concealed …
Pharmaceutical Application of Process Understanding and Optimization Techniques: A Review on the Continuous Twin-Screw Wet Granulation
J Zhao, G Tian, H Qu - Biomedicines, 2023 - mdpi.com
Twin-screw wet granulation (TSWG) is a method of continuous pharmaceutical
manufacturing and a potential alternative method to batch granulation processes. It has …
manufacturing and a potential alternative method to batch granulation processes. It has …