Hallmarks of cancer: of all cancer cells, all the time?
SL Floor, JE Dumont, C Maenhaut, E Raspe - Trends in molecular …, 2012 - cell.com
In two landmark articles, Hanahan and Weinberg synthesized into one conceptual
framework 'the hallmarks of cancer', a massive amount of information describing the …
framework 'the hallmarks of cancer', a massive amount of information describing the …
Characterizing dedifferentiation of thyroid cancer by integrated analysis
H Luo, X ** of the gastrointestinal microbiota identifies children with inflammatory bowel disease
Background Pediatric inflammatory bowel disease (IBD) is challenging to diagnose because
of the non-specificity of symptoms; an unequivocal diagnosis can only be made using …
of the non-specificity of symptoms; an unequivocal diagnosis can only be made using …
The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model
P Häfliger, J Graff, M Rubin, A Stooss… - Journal of experimental …, 2018 - Springer
Background The L-type amino acid transporter 1 (LAT1/SLC7A5) transports essential amino
acids across the plasma membrane. While LAT1 is overexpressed in a variety of human …
acids across the plasma membrane. While LAT1 is overexpressed in a variety of human …
Thyroid hormone receptor α1: a novel regulator of thyroid cancer cell differentiation
Thyroid hormone receptor α1 (TRα1) mediates the genomic actions of thyroid hormone (T3).
The biology of TRα1 in growth and development has been well studied, but the functional …
The biology of TRα1 in growth and development has been well studied, but the functional …
Deciphering radiological stable disease to immune checkpoint inhibitors
Background 'Stable disease (SD)'as per RECIST is a common but ambiguous outcome in
patients receiving immune checkpoint inhibitors (ICIs). This study aimed to characterize SD …
patients receiving immune checkpoint inhibitors (ICIs). This study aimed to characterize SD …
SREBP1 promotes invasive phenotypes by upregulating CYR61/CTGF via the Hippo-YAP pathway
CY Kuo, YC Chang, MN Chien… - Endocrine-Related …, 2022 - erc.bioscientifica.com
Aberrant lipid metabolism provides bioenergetic, biosynthetic, and redox supplies to cancer
cells. Previous studies have reported differential lipid profiling in thyroid malignancies. Sterol …
cells. Previous studies have reported differential lipid profiling in thyroid malignancies. Sterol …
Cancer-associated fibroblasts positively correlate with dedifferentiation and aggressiveness of thyroid cancer
S Wen, N Qu, B Ma, X Wang, Y Luo, W Xu… - OncoTargets and …, 2021 - Taylor & Francis
Background and Objectives Targeting cancer-associated fibroblast (CAF) is being explored
as an approach to improve cancer therapies. The roles of CAF remain unclarified in …
as an approach to improve cancer therapies. The roles of CAF remain unclarified in …
Characterization of immune landscape in papillary thyroid cancer reveals distinct tumor immunogenicity and implications for immunotherapy
Although the vast majority of patients with papillary thyroid cancer (PTC) have a favorable
prognosis when conventional treatments are implemented, local recurrence and distant …
prognosis when conventional treatments are implemented, local recurrence and distant …