Abstract Machine learning is increasingly important in microbiology where it is used for tasks
such as predicting antibiotic resistance and associating human microbiome features with …

A wide array of microorganisms, including many novel, phylogenetically deeply rooted taxa,
survive and thrive in extreme environments. These unique and reduced-complexity …

The accrual of genomic data from both cultured and uncultured microorganisms provides
new opportunities to develop systematic taxonomies based on evolutionary relationships …

Despite the surge of microbial genome data, experimental testing is important to confirm
inferences about the cell biology, ecological roles and evolution of microorganisms. As the …

Compared to bacteria, our knowledge of archaeal biology is limited. Historically,
microbiologists have mostly relied on culturing and single-gene diversity surveys to …

CRISPR-Cas systems provide microbes with adaptive immunity to infectious nucleic acids
and are widely employed as genome editing tools. These tools use RNA-guided Cas …

Challenges in cultivating microorganisms have limited the phylogenetic diversity of currently
available microbial genomes. This is being addressed by advances in sequencing …

Background Soil microbiomes play an important role in the services and functioning of
terrestrial ecosystems. However, little is known of their vertical responses to restoration …

The recent recovery of genomes for organisms from phyla with no isolated representative
(candidate phyla) via cultivation-independent genomics enabled delineation of major new …

The origin and cellular complexity of eukaryotes represent a major enigma in biology.
Current data support scenarios in which an archaeal host cell and an alphaproteobacterial …