Since their original discovery as regulators of follicle-stimulating hormone (FSH) secretion
and erythropoiesis, the TGF-β family members activin and inhibin have been shown to …

The local actions of the inhibin-related peptides inhibin, activin, and follistatin in
folliculogenesis, luteinization and atresia are reviewed. On the basis of in vitro data, it is …

Emerging additive manufacturing techniques enable investigation of the effects of pore
geometry on cell behavior and function. Here, we 3D print microporous hydrogel scaffolds to …

The endocrine system dynamically controls tissue differentiation and homeostasis, but has
not been studied using dynamic tissue culture paradigms. Here we show that a microfluidic …

To investigate further brain-pituitary-gonadal interrelationships we have generated mice in
which the gene encoding the FSH receptor has been disrupted. Female FSH receptor …

When it was initially discovered in 1923, inhibin was characterized as a hypophysiotropic
hormone that acts on pituitary cells to regulate pituitary hormone secretion. Ninety years …

The pituitary gonadotropins FSH and LH are key hormones for regulating gametogenesis
and steroidogenesis in the ovary and testis. The cell surface receptors that mediate the …

The regulation of reproductive processes involves a complex network of communication
systems between the brain, endocrine organs, the gonads and other reproductive tissues …

Granulosa cell tumors of the ovary (GCT) comprise a distinct subset of ovarian cancers that
account for approximately 5% of all ovarian malignancies. They are thought to arise from …

In vitro ovarian follicle cultures may provide fertility-preserving options to women facing
premature infertility due to cancer therapies. An encapsulated three-dimensional (3-D) …