[HTML][HTML] The association between oral hygiene and periodontitis: a systematic review and meta-analysis

A Lertpimonchai, S Rattanasiri… - International dental …, 2017 - Elsevier
Objective: Dental plaque accumulation and inadequate personal oral hygiene (OH) are
known major risk factors of periodontitis. Nevertheless, the magnitude of their effects has not …

Antimicrobial defense systems in saliva

W van't Hof, EC Veerman… - Monogr Oral …, 2014 - books.google.com
The oral cavity is one of the most heavily colonized parts of our body. The warm, nutrient-rich
and moist environment promotes the growth of a diverse microflora. One of the factors …

Expression and function of host defense peptides at inflammation sites

SV Prasad, K Fiedoruk, T Daniluk, E Piktel… - International journal of …, 2020 - mdpi.com
There is a growing interest in the complex role of host defense peptides (HDPs) in the
pathophysiology of several immune-mediated inflammatory diseases. The physicochemical …

Saliva as a diagnostic tool for dental caries, periodontal disease and cancer: is there a need for more biomarkers?

MAR Buzalaf, AC Ortiz, TS Carvalho… - Expert review of …, 2020 - Taylor & Francis
Introduction: A biomarker is a biological indicator of normal or pathogenic processes.
Identification of biomarkers is useful for the prevention, diagnosis and prognosis of diseases …

Diverse functions of defensins and other antimicrobial peptides in periodontal tissues

H Dommisch, S Jepsen - Periodontology 2000, 2015 - Wiley Online Library
Defensins are antimicrobial peptides that exhibit direct microbicidal activity as well as
mediator‐like functions by, for example, activating immature dendritic cells. This review …

Salivary antimicrobial peptides in early detection of periodontitis

GN Güncü, D Yilmaz, E Könönen… - Frontiers in cellular and …, 2015 - frontiersin.org
In the pathogenesis of periodontitis, an infection-induced inflammatory disease of the tooth-
supporting tissues, there is a complex interaction between the subgingival microbiota and …

Salivary human beta-defensins and cathelicidin levels in relation to periodontitis and type 2 diabetes mellitus

D Yilmaz, AO Topcu, EU Akcay, M Altındis… - Acta Odontologica …, 2020 - Taylor & Francis
Objective: Type 2 diabetes mellitus (T2DM) is a well-defined risk factor of periodontitis and it
can affect expression of human beta-defensins (hBDs) and cathelicidin (LL-37) as well. The …

Cationic antimicrobial peptides and periodontal physiopathology: A systematic review

ML Jourdain, F Velard, L Pierrard… - Journal of …, 2019 - Wiley Online Library
The purpose of this systematic review was to establish if patients suffering from periodontal
diseases present differences in the expression or production of cationic antimicrobial …

Roles of a mast cell–specific receptor MRGPRX2 in host defense and inflammation

C Chompunud Na Ayudhya, S Roy… - Journal of Dental …, 2020 - journals.sagepub.com
Mast cells are multifunctional immune cells that are found most abundantly at host-
environment interfaces, such as the skin, respiratory tract, and oral/gastrointestinal mucosa …

[HTML][HTML] Low DEFB4 copy number and high systemic hBD-2 and IL-22 levels are associated with dermatophytosis

SW Jaradat, S Cubillos, N Krieg, K Lehmann… - Journal of Investigative …, 2015 - Elsevier
Dermatophytes initiate dermatophytosis, but susceptibility to infection is dictated by host
genetic factors, although the role of some of these—such as human beta-defensin 2 (hBD-2) …