Angiogenesis in life, disease and medicine
P Carmeliet - Nature, 2005 - nature.com
The growth of blood vessels (a process known as angiogenesis) is essential for organ
growth and repair. An imbalance in this process contributes to numerous malignant …
growth and repair. An imbalance in this process contributes to numerous malignant …
Molecular regulation of angiogenesis and lymphangiogenesis
RH Adams, K Alitalo - Nature reviews Molecular cell biology, 2007 - nature.com
Blood vessels and lymphatic vessels form extensive networks that are essential for the
transport of fluids, gases, macromolecules and cells within the large and complex bodies of …
transport of fluids, gases, macromolecules and cells within the large and complex bodies of …
Vascular heterogeneity and specialization in development and disease
M Potente, T Mäkinen - Nature Reviews Molecular Cell Biology, 2017 - nature.com
Blood and lymphatic vessels pervade almost all body tissues and have numerous essential
roles in physiology and disease. The inner lining of these networks is formed by a single …
roles in physiology and disease. The inner lining of these networks is formed by a single …
[HTML][HTML] Lymphangiogenesis: molecular mechanisms and future promise
T Tammela, K Alitalo - Cell, 2010 - cell.com
The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of
pathological processes including tissue inflammation and tumor dissemination but is …
pathological processes including tissue inflammation and tumor dissemination but is …
The lymphatic vasculature in disease
K Alitalo - Nature medicine, 2011 - nature.com
Blood vessels form a closed circulatory system, whereas lymphatic vessels form a one-way
conduit for tissue fluid and leukocytes. In most vertebrates, the main function of lymphatic …
conduit for tissue fluid and leukocytes. In most vertebrates, the main function of lymphatic …
[HTML][HTML] Lymphatic vessel network structure and physiology
The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …
which has the holistic function to maintain the local physiologic environment for every cell in …
Lymphangiogenesis in development and human disease
The lymphatic vasculature forms a vessel network that drains interstitial fluid from tissues
and returns it to the blood. Lymphatic vessels are also an essential part of the body's …
and returns it to the blood. Lymphatic vessels are also an essential part of the body's …
Lymphatic malformations: genetics, mechanisms and therapeutic strategies
Lymphatic vessels maintain tissue fluid homeostasis by returning to blood circulation
interstitial fluid that has extravasated from the blood capillaries. They provide a trafficking …
interstitial fluid that has extravasated from the blood capillaries. They provide a trafficking …
Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer
The interstitium describes the fluid, proteins, solutes, and the extracellular matrix (ECM) that
comprise the cellular microenvironment in tissues. Its alterations are fundamental to …
comprise the cellular microenvironment in tissues. Its alterations are fundamental to …
Functionally specialized junctions between endothelial cells of lymphatic vessels
Recirculation of fluid and cells through lymphatic vessels plays a key role in normal tissue
homeostasis, inflammatory diseases, and cancer. Despite recent advances in understanding …
homeostasis, inflammatory diseases, and cancer. Despite recent advances in understanding …